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Antimicrobial properties of phenolic acid alkyl esters

Author

Listed:
  • Eva Feldeková
  • Michaela Kosová

    (Department of Dairy, Fat and Cosmetics, University of Chemistry and Technology Prague, Prague, Czech Republic)

  • Markéta Berčíková

    (Department of Dairy, Fat and Cosmetics, University of Chemistry and Technology Prague, Prague, Czech Republic)

  • Miroslav Dragoun

    (Department of Dairy, Fat and Cosmetics, University of Chemistry and Technology Prague, Prague, Czech Republic)

  • Iveta Klojdová

    (Department of Dairy, Fat and Cosmetics, University of Chemistry and Technology Prague, Prague, Czech Republic)

  • Iveta Hrádková

    (Department of Dairy, Fat and Cosmetics, University of Chemistry and Technology Prague, Prague, Czech Republic)

  • Jan Šmidrkal

    (Department of Dairy, Fat and Cosmetics, University of Chemistry and Technology Prague, Prague, Czech Republic)

Abstract

The series of phenolic acid (2-, 3-, 4-monohydroxy- and 2,4-, 2,5-dihydroxy) alkyl esters (methyl, ethyl, propyl, and butyl) were prepared, and their antimicrobial activities were determined. The antimicrobial activity against the tested microorganisms Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans and Aspergillus brasiliensis was investigated and expressed by minimum inhibitory concentration (MIC) in the range of 1.2-20 mM. The inhibitory activity of higher esters of phenolic acids was found to be higher than that of methyl esters and acids. The minimum inhibitory concentration (MIC) of tested compounds was compared with that of 4-hydroxybenzoic acid and its esters (parabens).

Suggested Citation

  • Eva Feldeková & Michaela Kosová & Markéta Berčíková & Miroslav Dragoun & Iveta Klojdová & Iveta Hrádková & Jan Šmidrkal, 2022. "Antimicrobial properties of phenolic acid alkyl esters," Czech Journal of Food Sciences, Czech Academy of Agricultural Sciences, vol. 40(6), pages 438-444.
  • Handle: RePEc:caa:jnlcjf:v:40:y:2022:i:6:id:135-2022-cjfs
    DOI: 10.17221/135/2022-CJFS
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    References listed on IDEAS

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    1. Roman Merkl & Iveta Hrádková & Vladimír Filip & Jan Šmidrkal, 2010. "Antimicrobial and antioxidant properties of phenolic acids alkyl esters," Czech Journal of Food Sciences, Czech Academy of Agricultural Sciences, vol. 28(4), pages 275-279.
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