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Sodium cholate sorption on N-octadecylpectinamide in comparison with cholestyramine

Author

Listed:
  • Andriy Synytsya

    (Department of Carbohydrate Chemistry and Technology, Faculty of Food and Biochemical Technology, Institute of Chemical Technology Prague, Prague, Czech Republic)

  • Lucie Fesslová

    (Department of Carbohydrate Chemistry and Technology, Faculty of Food and Biochemical Technology, Institute of Chemical Technology Prague, Prague, Czech Republic)

  • Milan Marounek

    (Department of Carbohydrate Chemistry and Technology, Faculty of Food and Biochemical Technology, Institute of Chemical Technology Prague, Prague, Czech Republic)

  • Jana Čopíková

    (Department of Carbohydrate Chemistry and Technology, Faculty of Food and Biochemical Technology, Institute of Chemical Technology Prague, Prague, Czech Republic)

Abstract

N-Octadecylpectinamide is hydrophobically modified HM citrus pectin. Previously, it had been prepared by heterogeneous amino-de-alkoxylation of initial pectin with n-octadecylamine in dimethylsulphoxide and characterised as potential hydrophobic sorbent and cholesterol lowering agent. The sorption properties of N-octadecylpectinamide were analysed in comparison with cholestyramine, an effective bile acid sequestrant. Sorption experiments were carried out using sodium cholate as a model bile acid. Cholate concentration was estimated by enzymatic spectroscopic method. Sorption kinetics curves and sorption isotherms of both sorbents were constructed and analysed.

Suggested Citation

  • Andriy Synytsya & Lucie Fesslová & Milan Marounek & Jana Čopíková, 2007. "Sodium cholate sorption on N-octadecylpectinamide in comparison with cholestyramine," Czech Journal of Food Sciences, Czech Academy of Agricultural Sciences, vol. 25(1), pages 32-38.
    • Handle: RePEc:caa:jnlcjf:v:25:y:2007:i:1:id:739-cjfs
    DOI: 10.17221/739-CJFS
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    References listed on IDEAS

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    1. A. Syntsya & J. Čpíková & M. Marounek & P. Mlčochová & L. Sihelková & P. Blafková & M. Tkadlecová & J. Havlíček, 2003. "Preparation of N-alkylamides of highly methylated (HM) citrus pectin," Czech Journal of Food Sciences, Czech Academy of Agricultural Sciences, vol. 21(5), pages 162-166.
    2. L. Sihelniková & A. Synytsya & J. Čopíková, 2004. "Amino-dealkoxylation of hm citruc pectin with n-alkylamines: a kinetic study," Czech Journal of Food Sciences, Czech Academy of Agricultural Sciences, vol. 22(SpecialIs), pages 235-237.
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