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Antioxidant activity of 2,6-dimethyl-3,5-dialkoxycarbonyl-1,4-dihydropyridines in metal-ion catalyzed lipid peroxidation

Author

Listed:
  • G. Tirzitis

    (Latvian Institute of Organic Synthesis, Riga, Latvia)

  • D. Tirzite

    (Latvian Institute of Organic Synthesis, Riga, Latvia)

  • Z. Hyvonen

    (Latvian Institute of Organic Synthesis, Riga, Latvia)

Abstract

Antioxidants with 1,4-dihydropyridine structure were investigated as a less harmful alternative to synthetic phenolic antioxidants in liposomes under conditions simulating food storage. The antioxidant activities (AOA) of 2,6-dimethyl-3,5-dialkoxycarbonyl-1,4-dihydropyridines possessing various side chain length alkyls (CH3 - C16H33) in ester moiety were tested in transition metal-ion catalyzed liposome peroxidation and compared with AOA of Trolox™ and Probucol™. The compounds with C2H5 - C4H9 residues in the 3,5-position ester moieties exert the most pronounced AOA. The AOA of tested compounds is associated with their ability to incorporate into liposomes.

Suggested Citation

  • G. Tirzitis & D. Tirzite & Z. Hyvonen, 2001. "Antioxidant activity of 2,6-dimethyl-3,5-dialkoxycarbonyl-1,4-dihydropyridines in metal-ion catalyzed lipid peroxidation," Czech Journal of Food Sciences, Czech Academy of Agricultural Sciences, vol. 19(3), pages 81-84.
    • Handle: RePEc:caa:jnlcjf:v:19:y:2001:i:3:id:6581-cjfs
    DOI: 10.17221/6581-CJFS
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    Cited by:

    1. Z.Y. Niu & F.Z. Liu & Y.N. Min & W.C. Li, 2010. "Effects of dietary dihydropyridine supplementation on growth performance and lipid metabolism of broiler chickens," Czech Journal of Animal Science, Czech Academy of Agricultural Sciences, vol. 55(3), pages 116-122.

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