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Characterization of c‐, L‐ and ϕk‐optimal designs for a class of non‐linear multiple‐regression models

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  • Dennis Schmidt

Abstract

Optimal designs for multiple‐regression models are determined. We consider a general class of non‐linear models including proportional hazards models with different censoring schemes, the Poisson and the negative binomial model. For these models we provide a complete characterization of c‐optimal designs for all vectors c in the case of a single covariate. For multiple regression with an arbitrary number of covariates, c‐optimal designs for certain vectors c are derived analytically. Using some general results on the structure of optimal designs for multiple regression, we determine L‐ and ϕk‐optimal designs for models with an arbitrary number of covariates.

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  • Dennis Schmidt, 2019. "Characterization of c‐, L‐ and ϕk‐optimal designs for a class of non‐linear multiple‐regression models," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 81(1), pages 101-120, February.
  • Handle: RePEc:bla:jorssb:v:81:y:2019:i:1:p:101-120
    DOI: 10.1111/rssb.12292
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