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Dose Finding Using the Biased Coin Up-and-Down Design and Isotonic Regression

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  • Mario Stylianou
  • Nancy Flournoy

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  • Mario Stylianou & Nancy Flournoy, 2002. "Dose Finding Using the Biased Coin Up-and-Down Design and Isotonic Regression," Biometrics, The International Biometric Society, vol. 58(1), pages 171-177, March.
  • Handle: RePEc:bla:biomet:v:58:y:2002:i:1:p:171-177
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    File URL: http://hdl.handle.net/10.1111/j.0006-341X.2002.00171.x
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    Cited by:

    1. Keshvari, Abolfazl & Kuosmanen, Timo, 2013. "Stochastic non-convex envelopment of data: Applying isotonic regression to frontier estimation," European Journal of Operational Research, Elsevier, vol. 231(2), pages 481-491.
    2. Guosheng Yin & Ying Yuan, 2009. "Bayesian dose finding in oncology for drug combinations by copula regression," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 58(2), pages 211-224, May.
    3. Anastasia Ivanova, 2003. "A New Dose-Finding Design for Bivariate Outcomes," Biometrics, The International Biometric Society, vol. 59(4), pages 1001-1007, December.
    4. Nancy Flournoy & José Moler & Fernando Plo, 2020. "Performance Measures in Dose‐Finding Experiments," International Statistical Review, International Statistical Institute, vol. 88(3), pages 728-751, December.
    5. Jiajing Xu & Guosheng Yin & David Ohlssen & Frank Bretz, 2016. "Bayesian two-stage dose finding for cytostatic agents via model adaptation," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 65(3), pages 465-482, April.
    6. Mark R. Conaway & Stephanie Dunbar & Shyamal D. Peddada, 2004. "Designs for Single- or Multiple-Agent Phase I Trials," Biometrics, The International Biometric Society, vol. 60(3), pages 661-669, September.
    7. Guosheng Yin & Ying Yuan, 2009. "A Latent Contingency Table Approach to Dose Finding for Combinations of Two Agents," Biometrics, The International Biometric Society, vol. 65(3), pages 866-875, September.

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