IDEAS home Printed from https://ideas.repec.org/a/bjc/journl/v9y2022i3p37-46.html
   My bibliography  Save this article

Combined Effect of Ethanolic Leaf Extracts of Carica Papaya and Newbouldia Laevis on Hematological Parameters and Sperm Quality of Alloxan-Induced Rats

Author

Listed:
  • Ifegwu Njoku Oji

    (Department of Anatomy, College of Medicine and Health Sciences, Abia State University Uturu, Abia State, Nigeria.)

  • Agbai Johnson Ukwa

    (Department of Anatomy, College of Medicine and Health Sciences, Abia State University Uturu, Abia State, Nigeria.)

  • Njoku-Oji Njideka Nancy

    (Department of Human Physiology, Faculty of Basic Medical Sciences, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria.)

  • Elem Chambelin Jamike

    (Department of Anatomy, College of Medicine and Health Sciences, Abia State University Uturu, Abia State, Nigeria.)

  • Aligwekwe Athanasius Ugochukwu

    (Department of Anatomy, Madonna University, Elele Campus, Nigeria.)

  • Ohaeri Esther Adaukwu

    (Department of Biochemistry, Abia State University, Uturu, Abia State, Nigeria.)

Abstract

Objective: This study was carried out to investigate the effect of ethanolic leaf extracts of C. papaya and N. laevis on hematological parameters and sperm quality of alloxan-induced diabetic wistar rats. Methodology: Forty male rats weighing 130-180g were procured, acclimatized for two weeks, after which, were divided into eight groups of five rats each, and were housed in cages. The groups were designated as groups A – H. Group A served as the control group and received distilled water only. Groups B – H were induced with diabetes using alloxan. Group B did not receive any treatment, while the groups C – H received 400mg/kg of C. papaya leaf extract, 600mg/kg of C. papaya leaf extract, 400mg/kg of N. laevis leaf extract, 600mg/kg of N. laevis leaf extract, 200mg/kg of C. papaya + 200mg/kg of N. laevis, and 300mg/kg of C. papaya + 300mg/kg of N. laevis leaf extract respectively for 21 days orally with oral gastric tube. On the 22nd day, the animals were sacrificed via chloroform inhalation and blood samples were collected through ocular puncture for hematological analyses, and epididymis were collected for sperm quality study. All data were tabulated and statistically analyzed using SPSS version 25.0. Result: The levels of WBC, RBC, HGB, PCV, sperm motility and sperm count were significantly (P

Suggested Citation

  • Ifegwu Njoku Oji & Agbai Johnson Ukwa & Njoku-Oji Njideka Nancy & Elem Chambelin Jamike & Aligwekwe Athanasius Ugochukwu & Ohaeri Esther Adaukwu, 2022. "Combined Effect of Ethanolic Leaf Extracts of Carica Papaya and Newbouldia Laevis on Hematological Parameters and Sperm Quality of Alloxan-Induced Rats," International Journal of Research and Scientific Innovation, International Journal of Research and Scientific Innovation (IJRSI), vol. 9(3), pages 37-46, March.
    • Handle: RePEc:bjc:journl:v:9:y:2022:i:3:p:37-46
    as

    Download full text from publisher

    File URL: https://www.rsisinternational.org/journals/ijrsi/digital-library/volume-9-issue-3/37-46.pdf
    Download Restriction: no
    File URL: https://www.rsisinternational.org/virtual-library/papers/combined-effect-of-ethanolic-leaf-extracts-of-carica-papaya-and-newbouldia-laevis-on-hematological-parameters-and-sperm-qaulity-of-alloxan-induced-rats/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Effrossyni Gkrania-Klotsas & Zheng Ye & Andrew J Cooper & Stephen J Sharp & Robert Luben & Mary L Biggs & Liang-Kung Chen & Kuppan Gokulakrishnan & Markolf Hanefeld & Erik Ingelsson & Wen-An Lai & Shi, 2010. "Differential White Blood Cell Count and Type 2 Diabetes: Systematic Review and Meta-Analysis of Cross-Sectional and Prospective Studies," PLOS ONE, Public Library of Science, vol. 5(10), pages 1-11, October.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.

      More about this item

      Statistics

      Access and download statistics

      Corrections

      All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:bjc:journl:v:9:y:2022:i:3:p:37-46. See general information about how to correct material in RePEc.

      If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

      If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

      If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

      For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Dr. Renu Malsaria (email available below). General contact details of provider: https://rsisinternational.org/journals/ijrsi/ .

      Please note that corrections may take a couple of weeks to filter through the various RePEc services.

      IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.