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The Effects of Consumption of Cashew Nut (Anacardium Occidentale) Diet on Scopolamine Induced Depression and Anxiety in CD1 Mice

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  • Johnbull Martins Uket

    (Department of Physiology, Faculty of Basic Medical Sciences, College of Medical Sciences, University of Calabar, Nigeria.)

  • Christiana Godwin Gekpe

    (Department of Physiology, Faculty of Basic Medical Sciences, College of Medical Sciences, University of Calabar, Nigeria.)

  • Helyn Andonimye Ikem

    (Department of Physiology, Faculty of Basic Medical Sciences, College of Medical Sciences, University of Calabar, Nigeria.)

  • Peter Cecilia Agbo

    (Department of Physiology, Faculty of Basic Medical Sciences, College of Medical Sciences, University of Calabar, Nigeria.)

  • Nkwa Oge

    (Department of physiology, faculty of medical sciences, Abia state university, Uturu , Nigeria)

Abstract

Cashew nut (Anacardium occidentale) contain vitamin B6, essential amino acids (tryptophan) a precursor of serotonin and omega-3 fatty acid which had been known to affect mood. However, whether consumption of cashew nut diet which contains vitamin B6, tryptophan and omega-3 fatty acid will affect mood notably, anxiety and depression in mice has not been previously ascertained. Therefore, the effects of consumption of cashew nut (Anacardium occidentale) diets on scopolamine induced anxiety and depression in CD1 mice was studied. Twenty-eight (28) experimental mice were randomly assigned into 4 groups namely; control, cashew nut diet only, cashew nut diet + scopolamine and scopolamine only group. Forced swim test was used to assess for depression in the animals and open field maize, light/dark transition box and elevated plus maze was used to access anxiety. Results from force swim test showed that, depressive symptoms were decreased in scopolamine only treated group compared to control and other experimental groups (p

Suggested Citation

  • Johnbull Martins Uket & Christiana Godwin Gekpe & Helyn Andonimye Ikem & Peter Cecilia Agbo & Nkwa Oge, 2024. "The Effects of Consumption of Cashew Nut (Anacardium Occidentale) Diet on Scopolamine Induced Depression and Anxiety in CD1 Mice," International Journal of Research and Scientific Innovation, International Journal of Research and Scientific Innovation (IJRSI), vol. 11(6), pages 639-655, June.
    • Handle: RePEc:bjc:journl:v:11:y:2024:i:6:p:639-655
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