Author
Listed:
- Ordu, J I
(Department of Pharmaceutics and Pharmaceutical Technology Faculty of Pharmaceutical Sciences, University of Port Harcourt)
- Aguma, I F
(Department of Pharmaceutics and Pharmaceutical Technology Faculty of Pharmaceutical Sciences, University of Port Harcourt)
Abstract
Prevalence of tooth decay in individuals attributes to bacterial buildup in the mouth and inconsistent effectiveness of certain commercial toothpastes and this has prompted the formulation of herbal toothpaste. The formulation is crafted with diverse bases to address gingivitis, dental caries and plaque, hence the toothpaste consist of intricate blends of abrasives, surfactants, anticaries agents, tartar control elements, pH buffers, humectants and binders ensuring consistency, shape and product stability. The herbal toothpaste formulation was prepared, incorporating aloe vera and calcium carbonate extract from the shell of Buccinum undatum. The focus of the composition aims to investigate the antimicrobial potential of the actives (aloe vera and calcium carbonate) in the toothpaste using cultures of S. aureus, P. aeruginosa and K.pneumoniae (prevalent micro organisms in the oral cavity) and comparing with a reference standard ( Colgate toothpaste). Utilizing the hot liquid phase technology, the toothpaste was formulated, and then evaluated. The Physicochemical evaluation studies reveals the formulation to have such characteristics as pH-10, good foamability and abrasiveness, spreadability of 5.5 gcms-¹, viscosity-4600 cP and appreciable stability. Anti microbial studies indicated notable zone of inhibition for the selected organisms as: K.pneumoniae – 5.5 mm and P. aeruginosa – 5.0 mm with no effect on S.aureus. The formulated herbal toothpaste consisting of aloe vera and extracted calcium carbonate was observed to display appreciable antimicrobial and abrasive properties hence further study is required to enhance its acceptable application for potential oral effects, and consideration for long term public dental health use.
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