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Impact of highly active antiretroviral treatment on HIV seroincidence among men who have sex with men: San Francisco

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Listed:
  • Katz, M.H.
  • Schwarcz, S.K.
  • Kellogg, T.A.
  • Klausner, J.D.
  • Dilley, J.W.
  • Gibson, S.
  • McFarland, W.

Abstract

Objectives. This study assessed the countervailing effects on HIV incidence of highly active antiretroviral treatment (HAART) among San Francisco men who have sex with men (MSM). Methods. Behavioral risk was determined on the basis of responses to cross-sectional community interviews. HIV incidence was assessed through application of an enzyme-linked immunoassay testing strategy. Results. Use of HAART among MSM living with AIDS increased from 4% in 1995 to 54% in 1999. The percentage of MSM who reported both unprotected anal intercourse and multiple sexual partners increased from 24% in 1994 to 45% in 1999. The annual HIV incidence rate increased from 2.1% in 1996 to 4.2% in 1999 among MSM who sought anonymous HIV testing, and the rate was high (5.3%) but stable in a blinded survey of MSM seeking sexually transmitted disease services. Conclusions. Any decrease in per contact risk of HIV transmission due to HAART use appears to have been counterbalanced or overwhelmed by increases in the number of unsafe sexual episodes.

Suggested Citation

  • Katz, M.H. & Schwarcz, S.K. & Kellogg, T.A. & Klausner, J.D. & Dilley, J.W. & Gibson, S. & McFarland, W., 2002. "Impact of highly active antiretroviral treatment on HIV seroincidence among men who have sex with men: San Francisco," American Journal of Public Health, American Public Health Association, vol. 92(3), pages 388-394.
    • Handle: RePEc:aph:ajpbhl:2002:92:3:388-394_9
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    Cited by:

    1. Nagelkerke, Nico J.D. & De Vlas, Sake J., 2003. "The epidemiological impact of an HIV vaccine on the HIV/AIDS epidemic in Southern India," Policy Research Working Paper Series 2978, The World Bank.
    2. Elliot Marseille & James Kahn & Christian Pitter & Rebecca Bunnell & William Epalatai & Emmanuel Jawe & Willy Were & Jonathan Mermin, 2009. "The cost effectiveness of home-based provision of antiretroviral therapy in rural Uganda," Applied Health Economics and Health Policy, Springer, vol. 7(4), pages 229-243, December.
    3. Stéphane Mechoulan, 2006. "Risky Sexual Behavior, Testing and New HIV Treatments," Working Papers tecipa-239, University of Toronto, Department of Economics.
    4. Francis, Andrew M. & Mialon, Hugo M. & Peng, Handie, 2012. "In sickness and in health: Same-sex marriage laws and sexually transmitted infections," Social Science & Medicine, Elsevier, vol. 75(8), pages 1329-1341.
    5. Mead Over & Peter Heywood & Julian Gold & Indrani Gupta & Subhash Hira & Elliot Marseille, 2004. "HIV/AIDS Treatment and Prevention in India : Modeling the Cost and Consequences," World Bank Publications - Books, The World Bank Group, number 14916.

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