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Use of highly active antiretroviral therapy in a cohort of HIV-seropositive women

Author

Listed:
  • Cook, J.A.
  • Cohen, M.H.
  • Grey, D.
  • Kirstein, L.
  • Burke, J.
  • Anastos, K.
  • Palacio, H.
  • Richardson, J.
  • Wilson, T.E.
  • Young, M.

Abstract

Objectives. This study examined longitudinal trends in use of highly active antiretroviral therapy (HAART) among a cohort of HIV-positive participants in the Women's Interagency HIV Study. Methods. Beginning in 1994, 1690 HIV-positive women reported detailed information about their use of antiretroviral therapy at 6-month study visits. Multivariate logistic and Cox regression analyses were used to estimate the likelihood of antiretroviral therapy and HAART use among women with study visits preceding and following HAART availability. Results. Before the availability of HAART, the cohort's likelihood of any antiretroviral therapy use was associated with clinical indicators (CD4 count, viral load, symptom presence) as well as behavioral factors (abstaining from drug and alcohol use, participating in clinical trials). After HAART became commercially available, newly emerging predictors included college education, private insurance, absence of injection drug use history, and not being African American. Conclusions. After the penetration of HAART into this cohort, additional differences emerged between HAART users and nonusers. These findings can inform public health efforts to enhance women's access to the most effective types of therapy.

Suggested Citation

  • Cook, J.A. & Cohen, M.H. & Grey, D. & Kirstein, L. & Burke, J. & Anastos, K. & Palacio, H. & Richardson, J. & Wilson, T.E. & Young, M., 2002. "Use of highly active antiretroviral therapy in a cohort of HIV-seropositive women," American Journal of Public Health, American Public Health Association, vol. 92(1), pages 82-87.
    • Handle: RePEc:aph:ajpbhl:2002:92:1:82-87_0
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    Cited by:

    1. Bereket Yakob & Busisiwe Purity Ncama, 2016. "Correlates of perceived access and implications for health system strengthening – lessons from HIV/AIDS treatment and care services in Ethiopia," PLOS ONE, Public Library of Science, vol. 11(8), pages 1-19, August.
    2. Omar Galárraga & David S. Salkever & Judith A. Cook & Stephen J. Gange, 2010. "An instrumental variables evaluation of the effect of antidepressant use on employment among HIV‐infected women using antiretroviral therapy in the United States: 1996–2004," Health Economics, John Wiley & Sons, Ltd., vol. 19(2), pages 173-188, February.

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