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Risk factors for acute non-A, non-B hepatitis and their relationship to antibodies for hepatitis C virus: A case-control study

Author

Listed:
  • Mele, A.
  • Sagliocca, L.
  • Manzillo, G.
  • Converti, F.
  • Amoroso, P.
  • Stazi, M.A.
  • Ferrigno, L.
  • Rapicetta, M.
  • Franco, E.
  • Adamo, B.
  • Palumbo, F.
  • Sbreglia, C.
  • Pana, A.
  • Pasquini, P.

Abstract

A case-control study was carried out comparing 333 case subjects with non- A, non-B hepatitis and 1095 hospital control subjects. Of 333 case subjects, 197 (59%) were positive for hepatitis C antibody (anti-HCV). Excluding blood transfusion and intravenous drug use, surgical intervention and dental therapy were strongly associated with anti-HCV-positive cases: in particular, obstetric and gynecology surgical intervention was found to be strongly associated with HCV positivity (odds ratio [OR] = 32; 95% confidence interval [CI] = 7, 147). Raw shellfish consumption was a risk factor for anti-HCV- negative cases (OR = 2.2; 95% CI = 1.0, 5.1), thus suggesting an enterically transmitted virus in sporadic non-A, non-B hepatitis in Italy.

Suggested Citation

  • Mele, A. & Sagliocca, L. & Manzillo, G. & Converti, F. & Amoroso, P. & Stazi, M.A. & Ferrigno, L. & Rapicetta, M. & Franco, E. & Adamo, B. & Palumbo, F. & Sbreglia, C. & Pana, A. & Pasquini, P., 1994. "Risk factors for acute non-A, non-B hepatitis and their relationship to antibodies for hepatitis C virus: A case-control study," American Journal of Public Health, American Public Health Association, vol. 84(10), pages 1640-1643.
    • Handle: RePEc:aph:ajpbhl:1994:84:10:1640-1643_9
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