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The association of age-related macular degeneration and lens opacities in the aged

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  • Liu, I.Y.
  • White, L.
  • LaCroix, A.Z.

Abstract

Data from 3,087 persons age 45 or older in the National Health and Nutrition Survey, 1971-74, showed that subjects with lens opacifying disease had an increased odds for age-related macular degeneration (AMD) compared to those who had no lens opacities. The crude odds ratio for aphakic patients was 4.6 (95% CI = 2.5, 8.6). The association remained after controlling for age, sex, and systolic blood pressure (a common risk factor) in a logistic regression model. These data are consistent with the hypothesis that light-induced damage may contribute to both lens and retinal disease and suggest that cataract extraction without implantation of ultra-violet/blue light absorbing intraocular lens may place subjects at increased risk of AMD.

Suggested Citation

  • Liu, I.Y. & White, L. & LaCroix, A.Z., 1989. "The association of age-related macular degeneration and lens opacities in the aged," American Journal of Public Health, American Public Health Association, vol. 79(6), pages 765-769.
    • Handle: RePEc:aph:ajpbhl:1989:79:6:765-769_0
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    Cited by:

    1. Declan Timothy Waugh, 2019. "The Contribution of Fluoride to the Pathogenesis of Eye Diseases: Molecular Mechanisms and Implications for Public Health," IJERPH, MDPI, vol. 16(5), pages 1-28, March.

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