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Evaluation of the relationship of sodium in drinking water and toxemia of pregnancy

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  • Jones, R.F.
  • Cech, I.I.
  • Holguin, A.H.
  • Hardy, R.J.

Abstract

This study is a retrospective case comparison analysis of the relationship of water-borne Na+ and toxemia of pregnancy as a part of a continuous investigation at our facility on the role of various water constituents in human chronic disease. Five hundred thirty-seven toxemic pregnant women delivered at Jefferson Davis Hospital, Houston, Texas, during 1976 were matched by age, race, obstetrical history, and month of delivery to 537 non-toxemic controls. Sodium concentration in each patient's drinking water was derived, based on her address, from earlier prepared maps of sodium distribution in Houston's water supplies. Paired t-tests were performed to compare the Na+ levels, which varied from 19 to 250 mg/l in water supplies of cases and controls. Odds ratio analysis was used to test for the presence of a gradient in occurrence of toxemia in parallel with the gradient of Na+. No significant impact of water-borne Na+ in the indicated range was observed. Further studies incorporating still higher ranges are contemplated.

Suggested Citation

  • Jones, R.F. & Cech, I.I. & Holguin, A.H. & Hardy, R.J., 1979. "Evaluation of the relationship of sodium in drinking water and toxemia of pregnancy," American Journal of Public Health, American Public Health Association, vol. 69(9), pages 917-921.
    • Handle: RePEc:aph:ajpbhl:10.2105/ajph.69.9.917_9
    DOI: 10.2105/AJPH.69.9.917
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