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Origin, methods, and evolution of the three nurses' health studies

Author

Listed:
  • Bao, Y.
  • Bertoia, M.L.
  • Lenart, E.B.
  • Stampfer, M.J.
  • Willett, W.C.
  • Speizer, F.E.
  • Chavarro, J.E.

Abstract

We have summarized the evolution of the Nurses' Health Study (NHS), a prospective cohort study of 121 700 married registered nurses launched in 1976; NHS II, which began in 1989 and enrolled 116 430 nurses; and NHS3, which began in 2010 and has ongoing enrollment. Over 40 years, these studies have generated long- Term, multidimensional data, including lifestyle- And health-related information across the life course and an extensive repository of various biological specimens.We have described the questionnaire data collection, disease followup methods, biorepository resources, and data management and statistical procedures. Through integrative analyses, these studies have sustained a high level of scientific productivity and substantially influenced public health recommendations. We have highlighted recent interdisciplinary research projects and discussed future directions for collaboration and innovation.

Suggested Citation

  • Bao, Y. & Bertoia, M.L. & Lenart, E.B. & Stampfer, M.J. & Willett, W.C. & Speizer, F.E. & Chavarro, J.E., 2016. "Origin, methods, and evolution of the three nurses' health studies," American Journal of Public Health, American Public Health Association, vol. 106(9), pages 1573-1581.
    • Handle: RePEc:aph:ajpbhl:10.2105/ajph.2016.303338_4
    DOI: 10.2105/AJPH.2016.303338
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    Cited by:

    1. Bin Xia & Qiangsheng He & Fang Gao Smith & V. Georgios Gkoutos & Krishnarajah Nirantharakumar & Zi Chong Kuo & Danni Wang & Qi Feng & Eddie C. Cheung & Lunzhi Dai & Junjie Huang & Yuanyuan Yu & Wenbo , 2024. "Individualized prevention of proton pump inhibitor related adverse events by risk stratification," Nature Communications, Nature, vol. 15(1), pages 1-12, December.
    2. Fenglei Wang & Anne-Julie Tessier & Liming Liang & Clemens Wittenbecher & Danielle E. Haslam & Gonzalo Fernández-Duval & A. Heather Eliassen & Kathryn M. Rexrode & Deirdre K. Tobias & Jun Li & Oana Ze, 2023. "Plasma metabolomic profiles associated with mortality and longevity in a prospective analysis of 13,512 individuals," Nature Communications, Nature, vol. 14(1), pages 1-11, December.
    3. Beccia, Ariel L. & Baek, Jonggyu & Austin, S. Bryn & Jesdale, William M. & Lapane, Kate L., 2021. "Eating-related pathology at the intersection of gender identity and expression, sexual orientation, and weight status: An intersectional Multilevel Analysis of Individual Heterogeneity and Discriminat," Social Science & Medicine, Elsevier, vol. 281(C).

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