IDEAS home Printed from https://ideas.repec.org/a/aph/ajpbhl/10.2105-ajph.2016.303325_9.html
   My bibliography  Save this article

Breast cancer research in the nurses' health studies: Exposures across the life course

Author

Listed:
  • Rice, M.S.
  • Eliassen, A.H.
  • Hankinson, S.E.
  • Lenart, E.B.
  • Willett, W.C.
  • Tamimi, R.M.

Abstract

Objectives. To review the contribution of the Nurses' Heath Study (NHS) and the NHS II in identifying risk and protective factors for breast cancer incidence and survival. Methods.We conducted a narrative review of NHS and NHS II articles on breast cancer incidence and survival published from 1976 to 2016, with a focus on exogenous and endogenous hormones; lifestyle factors, including diet, physical activity, and aspirin use; intermediate markers of risk; and genetic factors. Results. With the investigation of individual risk factors, as well as their incorporation into risk predictionmodels, the NHS has contributed to the identification of ways in which women may reduce breast cancer risk, including limiting alcohol consumption, reducing the duration of postmenopausal estrogen-plus-progestin use, avoiding weight gain, and increasing vegetable consumption. In addition, the NHS has helped elucidate the roles of several biomarkers and contributed to the identification of risk alleles. Conclusions.The NHS has contributed to our understanding of lifestyle, hormonal, and genetic risk factors for breast cancer, highlighting the importance of exposures across the life course, and has helped identify lifestyle changes that may reduce risk and improve survival after a diagnosis of breast cancer.

Suggested Citation

  • Rice, M.S. & Eliassen, A.H. & Hankinson, S.E. & Lenart, E.B. & Willett, W.C. & Tamimi, R.M., 2016. "Breast cancer research in the nurses' health studies: Exposures across the life course," American Journal of Public Health, American Public Health Association, vol. 106(9), pages 1592-1598.
    • Handle: RePEc:aph:ajpbhl:10.2105/ajph.2016.303325_9
    DOI: 10.2105/AJPH.2016.303325
    as

    Download full text from publisher

    File URL: http://hdl.handle.net/10.2105/AJPH.2016.303325
    Download Restriction: no
    File URL: https://libkey.io/10.2105/AJPH.2016.303325?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:aph:ajpbhl:10.2105/ajph.2016.303325_9. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Christopher F Baum (email available below). General contact details of provider: https://www.apha.org .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.