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Estimating acute viral hepatitis infections from nationally reported cases

Author

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  • Klevens, R.M.
  • Liu, S.
  • Roberts, H.
  • Jiles, R.B.
  • Holmberg, S.D.

Abstract

Objectives. Because only a fraction of patients with acute viral hepatitis A, B, and C are reported through national surveillance to the Centers for Disease Control and Prevention, we estimated the true numbers. Methods. We applied a simple probabilistic model to estimate the fraction of patients with acute hepatitis A, hepatitis B, and hepatitis C who would have been symptomatic, would have sought health care tests, and would have been reported to health officials in 2011. Results. For hepatitis A, the frequencies of symptoms (85%), care seeking (88%), and reporting (69%) yielded an estimate of 2730 infections (2.0 infections per reported case). For hepatitis B, the frequencies of symptoms (39%), care seeking (88%), and reporting (45%) indicated 18 730 infections (6.5 infections per reported case). For hepatitis C, the frequency of symptoms among injection drug users (13%) and those infected otherwise (48%), proportion seeking care (88%), and percentage reported (53%) indicated 17 100 infections (12.3 infections per reported case). Conclusions. These adjustment factors will allow state and local health authorities to estimate acute hepatitis infections locally and plan prevention activities accordingly.

Suggested Citation

  • Klevens, R.M. & Liu, S. & Roberts, H. & Jiles, R.B. & Holmberg, S.D., 2014. "Estimating acute viral hepatitis infections from nationally reported cases," American Journal of Public Health, American Public Health Association, vol. 104(3), pages 482-487.
    • Handle: RePEc:aph:ajpbhl:10.2105/ajph.2013.301601_9
    DOI: 10.2105/AJPH.2013.301601
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    Cited by:

    1. John J. Jost & Barbara Tempalski & Tatiana Vera & Matthew J. Akiyama & Aprille P. Mangalonzo & Alain H. Litwin, 2019. "Gaps in HCV Knowledge and Risk Behaviors among Young Suburban People Who Inject Drugs," IJERPH, MDPI, vol. 16(11), pages 1-10, June.
    2. David Beheshti, 2019. "Adverse health effects of abuse‐deterrent opioids: Evidence from the reformulation of OxyContin," Health Economics, John Wiley & Sons, Ltd., vol. 28(12), pages 1449-1461, December.

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