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25-hydroxyvitamin D in the range of 20 to 100 ng/mL and incidence of kidney stones

Author

Listed:
  • Nguyen, S.
  • Baggerly, L.
  • French, C.
  • Heaney, R.P.
  • Gorham, E.D.
  • Garland, C.F.

Abstract

Objectives. Increasing 25-hydroxyvitamin D serum levels can prevent a wide range of diseases. There is a concern about increasing kidney stone risk with vitamin D supplementation. We used Grassroots Health data to examine the relationship between vitamin D status and kidney stone incidence. Methods. The study included 2012 participants followed prospectively for a median of 19 months. Thirteen individuals self-reported kidney stones during the study period. Multivariate logistic regression was applied to assess the association between vitamin D status and kidney stones. Results. We found no statistically significant association between serum 25-hydroxyvitamin D and kidney stones (P = .42). Body mass index was significantly associated with kidney stone risk (odds ratio = 3.5; 95% confidence interval = 1.1, 11.3). Conclusions. We concluded that a serum 25-hydroxyvitamin D level of 20 to 100 nanograms per milliliter has no significant association with kidney stone incidence.

Suggested Citation

  • Nguyen, S. & Baggerly, L. & French, C. & Heaney, R.P. & Gorham, E.D. & Garland, C.F., 2014. "25-hydroxyvitamin D in the range of 20 to 100 ng/mL and incidence of kidney stones," American Journal of Public Health, American Public Health Association, vol. 104(9), pages 1783-1787.
    • Handle: RePEc:aph:ajpbhl:10.2105/ajph.2013.301368_2
    DOI: 10.2105/AJPH.2013.301368
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