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Smoking and cognitive decline among middle-aged men and women: The Doetinchem Cohort Study

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  • Nooyens, A.C.J.
  • Van Gelder, B.M.
  • Verschuren, W.M.M.

Abstract

Objectives. We studied the effect of smoking on cognitive decline over a 5-year period at middle age (43 to 70 years). Methods. In the Doetinchem Cohort Study, 1964 men and women in the Netherlands were examined for cognitive function at baseline and 5 years later. The association between smoking status and memory function, speed of cognitive processes, cognitive flexibility, and global cognitive function were assessed. Results. At baseline, smokers scored lower than never smokers in global cognitive function, speed, and flexibility. At 5-year follow-up, decline among smokerswas 1.9 times greater for memory function, 2.4 times greater for cognitive flexibility, and 1.7 times greater for global cognitive function than among never smokers. Among ever smokers, the declines in all cognitive domains were larger with increasing number of pack-years smoked. Conclusions. Interventions to prevent or stop people from smoking may postpone cognitive decline in middle-aged persons.

Suggested Citation

  • Nooyens, A.C.J. & Van Gelder, B.M. & Verschuren, W.M.M., 2008. "Smoking and cognitive decline among middle-aged men and women: The Doetinchem Cohort Study," American Journal of Public Health, American Public Health Association, vol. 98(12), pages 2244-2250.
    • Handle: RePEc:aph:ajpbhl:10.2105/ajph.2007.130294_5
    DOI: 10.2105/AJPH.2007.130294
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    Cited by:

    1. Michal Steffl & Tereza Jandova & Klara Dadova & Iva Holmerova & Piergiusto Vitulli & Sante D. Pierdomenico & Tiziana Pietrangelo, 2019. "Demographic and Lifestyle Factors and Memory in European Older People," IJERPH, MDPI, vol. 16(23), pages 1-11, November.

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