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Directly observed highly active antiretroviral therapy for HIV-infected children in Cambodia

Author

Listed:
  • Myung, P.
  • Pugatch, D.
  • Brady, M.F.
  • Many, P.
  • Harwell, J.I.
  • Lurie, M.
  • Tucker, J.

Abstract

Antiretroviral medications are becoming available for HIV-infected children in resource-limited settings. Maryknoll, an international Catholic charity, provided directly observed antiretroviral therapy to HIV-infected children in Phnom Penh, Cambodia. Child care workers administered generic antiretroviral drugs twice daily to children, ensuring adherence. Treatment began with 117 late-stage HIV-infected children; 22 died of AIDS during the first 6 months. The rest were treated for at least 6 months and showed CD4 count increases comparable to those achieved in US and European children. Staffing cost for this program was approximately US $5 per child per month, or 15% more than the price of the medications. Drug toxicities were uncommon and easily managed. Directly observed antiretroviral therapy appears to be a promising, low-cost strategy for ensuring adherent treatment for HIV-infected children in a resource-limited setting.

Suggested Citation

  • Myung, P. & Pugatch, D. & Brady, M.F. & Many, P. & Harwell, J.I. & Lurie, M. & Tucker, J., 2007. "Directly observed highly active antiretroviral therapy for HIV-infected children in Cambodia," American Journal of Public Health, American Public Health Association, vol. 97(6), pages 974-977.
    • Handle: RePEc:aph:ajpbhl:10.2105/ajph.2005.083253_6
    DOI: 10.2105/AJPH.2005.083253
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