IDEAS home Printed from https://ideas.repec.org/a/aoj/lifscr/v2y2015i3p61-67id624.html
   My bibliography  Save this article

Neurophysiological Effect of Pentoxifyllin on Male Albino Rats

Author

Listed:
  • Somaya M.Ismail
  • Hayat A. Ismail

Abstract

The objective of the present work is to study the possibility of involved neurotransmitters in the CNS side effects due to the administration of Pentoxifyllin in male albino rats. The frontal cortex of Pentoxifyllin treated groups revealed decrease of glutamate, GABA and elevation of aspartate, asparagines, glycin, serine levels and AChE activities in a time related effect. In the hippocampus area there are elevation of asparaginet, GABA, glycine, serine level but reductions of glutamate, aspartate level and AChE activities in a time related effect. Overall, the data suggest that there is a shift in the balance between neurotranamitters towards increased production of excitatory potency in groups subjected to Pentoxifyllin administration.

Suggested Citation

  • Somaya M.Ismail & Hayat A. Ismail, 2015. "Neurophysiological Effect of Pentoxifyllin on Male Albino Rats," Journal of Life Sciences Research, Asian Online Journal Publishing Group, vol. 2(3), pages 61-67.
    • Handle: RePEc:aoj:lifscr:v:2:y:2015:i:3:p:61-67:id:624
    as

    Download full text from publisher

    File URL: http://asianonlinejournals.com/index.php/Lifsc/article/view/624/620
    Download Restriction: no
    ---><---

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:aoj:lifscr:v:2:y:2015:i:3:p:61-67:id:624. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sara Lim (email available below). General contact details of provider: http://asianonlinejournals.com/index.php/Lifsc/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.