IDEAS home Printed from https://ideas.repec.org/a/adp/joroaj/v14y2019i3p58-64.html
   My bibliography  Save this article

The Incidence of Serious Infections among Rheumatoid Arthritis Patients using Biological Agents

Author

Listed:
  • Yaman Walid Kassab
  • Aina Yazrin Ali
  • Hiba Khaled Al Dahoul

    (Department of Hospital and Clinical Pharmacy, Faculty of Pharmacy, Cyberjaya University College of Medical Sciences, 63000 Selangor, Malaysia)

  • Mohammed Salah Ayad
  • Nasreh Shamsi Poor Gheshmi
  • Fares MS Muthanna

    (Faculty of Pharmacy, University Teknologi MARA (UiTM), 42300 Bandar Puncak Alam, Selangor Darul Ehsan, Malaysia)

  • Ganesh Sritheran Paneerselvam

    (School of pharmacy, Taylor’s University, 47500 Subang Jaya, Selangor Darul Ehsan, Malaysia)

Abstract

Rheumatoid arthritis (RA) is a chronic, progressive inflammatory condition that can lead to significant disability and joint pain. Various studies have found that RA itself as well as the drugs used in its management (particularly immunosuppressants and steroids) may lead to serious infections (SI). Serious infections maybe defined as an infection that requires hospitalization with or without IV antibiotics or leading to significant disability/incapacity [1]. Many trials have shown that biological agents significantly control signs and symptoms, slow progression and improve function and quality of life of patients with early or long-standing RA [2]. However, biological agents also play an important role in host defense and may be associated with increased risk of serious infections (SI) [3-7].

Suggested Citation

  • Yaman Walid Kassab & Aina Yazrin Ali & Hiba Khaled Al Dahoul & Mohammed Salah Ayad & Nasreh Shamsi Poor Gheshmi & Fares MS Muthanna & Ganesh Sritheran Paneerselvam, 2019. "The Incidence of Serious Infections among Rheumatoid Arthritis Patients using Biological Agents," Orthopedics and Rheumatology Open Access Journals, Juniper Publishers Inc., vol. 14(3), pages 58-64, July.
    • Handle: RePEc:adp:joroaj:v:14:y:2019:i:3:p:58-64
    DOI: 10.19080/OROAJ.2019.14.555887
    as

    Download full text from publisher

    File URL: https://juniperpublishers.com/oroaj/pdf/OROAJ.MS.ID.555887.pdf
    Download Restriction: no
    File URL: https://juniperpublishers.com/oroaj/OROAJ.MS.ID.555887.php
    Download Restriction: no
    File URL: https://libkey.io/10.19080/OROAJ.2019.14.555887?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:adp:joroaj:v:14:y:2019:i:3:p:58-64. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Robert Thomas (email available below). General contact details of provider: .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.