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Giant Rheumatoid Synovial Cyst of the Plantar Foot Review and Case Report

Author

Listed:
  • Ronald Troxell

    (Department of Podiatry, Norton Audubon Hospital, USA)

  • Carl Kihm

    (Department of Podiatry, University Foot and Ankle, USA)

Abstract

Rheumatoid arthritis (RA) is a chronic, systemic, auto-immune disorder of unknown etiology. The condition is characterized by the degree of joint destruction, deformity and disability that it causes. The RA disease process begins in the synovial membrane of joints. Initially, the synovial tissue undergoes immune-mediated microvascular injury (venous distension, capillary obstruction and thrombosis, and peri-vascular hemorrhage) [1]. This results in a rheumatoid pannus - synovial tissue edema and synovial cell proliferation. The swollen, hypertrophied synovium protrudes into the surrounding joint where an immune-mediated cascade of events releases hydrolytic enzymes, oxygen radicals and arachidonic acid metabolites [1].

Suggested Citation

  • Ronald Troxell & Carl Kihm, 2018. "Giant Rheumatoid Synovial Cyst of the Plantar Foot Review and Case Report," Orthopedics and Rheumatology Open Access Journals, Juniper Publishers Inc., vol. 10(3), pages 53-56, February.
    • Handle: RePEc:adp:joroaj:v:10:y:2018:i:3:p:53-56
    DOI: 10.19080/OROAJ.2018.10.555791
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