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NSF-Funded Green Drug Discovery Research Program Based on a 90MHz NMR Spectrometer

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  • Joseph Kipronoh Rugutt

    (Department of Chemistry, Missouri State University-West, USA)

Abstract

My ongoing research is focused on green Diels-Alder nanosynthesis of bioactive chalcones [1] derived from medicinal plants endemic to Kenya [2-5]. The versatile Diels-Alder [4+2] cycloaddition [6] is an enviable asset in the organic chemist’s toolbox because it triggers the simultaneous setting of asymmetric centers, ring(s), and functional groups. Cong and co-workers [7] were the first to report the use of silver nanoparticle (AgNP) catalysts in the Diels-Alder total synthesis of the cytotoxic chalcone-based natural product panduratin A.

Suggested Citation

  • Joseph Kipronoh Rugutt, 2020. "NSF-Funded Green Drug Discovery Research Program Based on a 90MHz NMR Spectrometer," Organic & Medicinal Chemistry International Journal, Juniper Publishers Inc., vol. 10(3), pages 82-84, December.
    • Handle: RePEc:adp:jomcij:v:10:y:2020:i:3:p:82-84
    DOI: 10.19080/OMCIJ.2020.10.555786
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