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Neuroprotective Effects of Agmatine and Hippocampal Neuron Loss in the Depression

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  • Meng Yang Zhu

    (Department of Biomedical Sciences, East Tennessee State University, USA)

Abstract

Agmatine is anendogenous polyamine and potential neurotransmitter in the brain. This article reviewed the neuroprotective effects of agmatine on hippocampal neurons against glutamate and glucocorticoids-induced neuronal damage. As neuronal loss in the hippocampus is a characteristic of depression, the neuroprotective activity of agmatine may play important role in the pathophysiology of major depression.

Suggested Citation

  • Meng Yang Zhu, 2018. "Neuroprotective Effects of Agmatine and Hippocampal Neuron Loss in the Depression," Open Access Journal of Neurology & Neurosurgery, Juniper Publishers Inc., vol. 7(5), pages 105-108, May.
    • Handle: RePEc:adp:joajnn:v:7:y:2018:i:5:p:105-108
    DOI: 10.19080/OAJNN.2018.07.555725
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