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Leptomeningeal Carcinomatosis from Prostate Cancer

Author

Listed:
  • L Amaadour
  • Z Benbrahim
  • N Mellas

    (Department of medical oncology, Hassan II university hospital, Fez, Morocco)

Abstract

Leptomeningeal metastasis (LM) can complicate any malignant tumor. It can be seen mainly in patients with breast, lung cancer, and malignant melanoma. However, LM from prostate cancer is extremely rare [1]. The clinical presentation of LM is variable since all the levels of the neuro-axis may be affected. Meningeal symptoms include signs of intracranial hypertension like headache, vomiting bu also seizures, sensory abnormalities, memory problems as well asincontinence, asthenia, pain and confusion. Cranial nerve are commonly affected espacially the III, V, VI, VII and the VIII cranial nerves [1]. The gold standard for diagnosis relies on the presence of malignant cells in the cerebrospinal fluid. However, this complication may be highly suspected in the case of hypoglycorrhachia, lymphocytic pleocytosis, and elevated opening pressure. Meningeal enhancement in the MRI may also be very suggestive of the leptomeningeal metastasis [2].

Suggested Citation

  • L Amaadour & Z Benbrahim & N Mellas, 2018. "Leptomeningeal Carcinomatosis from Prostate Cancer," Open Access Journal of Neurology & Neurosurgery, Juniper Publishers Inc., vol. 7(1), pages 13-14, February.
    • Handle: RePEc:adp:joajnn:v:7:y:2018:i:1:p:13-14
    DOI: 10.19080/OAJNN.2018.07.555704
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