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GAMALATE B6. Review of a GABAergic Product

Author

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  • Julio J Secades

    (Scientific Department, Ferrer Group SA, Spain)

Abstract

To determine the LD50 of Gamalate B6 syrup, the experimentation animal chosen was the albino rat (Wistar), weighing between 180 and 200g. A group of 10 animals received the normal diet established in our laboratory. The administration of the active components of the specialty Gamalate B6 syrup was made through a gastric tube in a dilution at 12% in distilled water. With a dose of 6g/Kg of the active components, only one death occurred in 24h. This has been the highest dose administered, corresponding to 100cc/kg of the specialty Gamalate B6. Therefore, the LD50 of Gamalate B6 syrup by oral route in albino rat can be considered indeterminable.

Suggested Citation

  • Julio J Secades, 2017. "GAMALATE B6. Review of a GABAergic Product," Open Access Journal of Neurology & Neurosurgery, Juniper Publishers Inc., vol. 6(4), pages 98-101, December.
  • Handle: RePEc:adp:joajnn:v:6:y:2017:i:4:p:98-101
    DOI: 10.19080/OAJNN.2017.06.555696
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