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Fifty Years of Levodopa: Pitfalls and Outlook

Author

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  • Roberta Bonomo

    (Department GF Ingrassia and Section of Neurosciences, University of Catania, Italy)

Abstract

Parkinson’s Disease (PD) is a complex neurodegenerative condition manifested by characteristic motor impairment and non-motor symptoms. Levodopa represents the most effective treatment of PD. However, despite providing in the early stages of the disorder an efficacious control of the symptomatology, the beneficial effects of the treatment gradually decline. That determines the development of a wide array of motor complications which should be recognized by the physician for an optimization of the treatment over time. Nevertheless, the clinical management of complicated PD still results controversial, and the development of specific guidelines remains an unmet need.

Suggested Citation

  • Roberta Bonomo, 2019. "Fifty Years of Levodopa: Pitfalls and Outlook," Open Access Journal of Neurology & Neurosurgery, Juniper Publishers Inc., vol. 11(5), pages 102-103, October.
    • Handle: RePEc:adp:joajnn:v:11:y:2019:i:5:p:102-103
    DOI: 10.19080/OAJNN.2019.11.555824
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