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PNA: A Snapshot on their Applications in Leukemia Diagnosis and Research

Author

Listed:
  • Valentina Rosso
  • Jessica Petiti
  • Cristina Panuzzo

    (Contributed equally)

  • Daniela Cilloni

    (Department of Clinical and Biological Sciences, University of Turin, Turin, Italy)

Abstract

PNAs are oligomers with a backbone composed of N-(2- aminoethyl) glycine units. They are chemically stable and resistant to hydrolytic cleavage and can hybridize to complementary DNA and RNA. PNA also show greater specificity and are stable over a wide range of pH and temperature. The unique characteristics of PNAs have allowed the development of a lot of different biological assays. In our opinion paper, we summarized the PNA applications focusing on the diagnosis of leukemia.

Suggested Citation

  • Valentina Rosso & Jessica Petiti & Cristina Panuzzo & Daniela Cilloni, 2018. "PNA: A Snapshot on their Applications in Leukemia Diagnosis and Research," Open Access Blood Research & Transfusion Journal, Juniper Publishers Inc., vol. 2(1), pages 5-7, February.
    • Handle: RePEc:adp:joabtj:v:2:y:2018:i:1:p:5-7
    DOI: 10.19080/OABTJ.2018.02.555577
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    More about this item

    Keywords

    Open Access Blood Research Journal; Open Access Blood Research & Transfusion Journal; juniper publishers; Open Access ; Blood Research & Transfusion Journal; blood research impact factor; blood research topics; blood research paper; blood research & transfusion journa;
    All these keywords.

    JEL classification:

    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

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