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Coordination Complexes with Lignin-Based Nanoparticles in Targeted Drug Controlled Release and Their Molecular Expression in Cell Lines

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  • Muhammad Ferhan

    (Lignin Valorization & Nanomaterials Lab, University of the Punjab, Pakistan)

Abstract

By increasing environmental pollution and fossil fuel depletion has brought an attention for biorenewable and environmentally friendly materials. Among biorenewable polymers, lignin is the second most abundant polymer after cellulose. Lignin nanoparticles can work as bio-carriers for drug delivery by coordinating complex formation with metal ions. A rapid innovation of nanotechnology has elevated the opportunity by using tailored lignin coordinated nanoparticles that interrelate in biological environments for targeting drug delivery. With controlled release in safe existing conditions, the nano encapsulation of dynamic substances has been encouraged of various rational activities mainly because of biopharmaceutical potential of such efforts. The extracellular matrix can activate a series of biological outcomes while nanoparticles interact with cells.

Suggested Citation

  • Muhammad Ferhan, 2017. "Coordination Complexes with Lignin-Based Nanoparticles in Targeted Drug Controlled Release and Their Molecular Expression in Cell Lines," Novel Approaches in Drug Designing & Development, Juniper Publishers Inc., vol. 1(2), pages 24-31, May.
    • Handle: RePEc:adp:jnapdd:v:1:y:2017:i:2:p:24-31
    DOI: 10.19080/NAPDD.2017.01.555559
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    References listed on IDEAS

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    1. Yue Lu & Quanyin Hu & Yiliang Lin & Dennis B. Pacardo & Chao Wang & Wujin Sun & Frances S. Ligler & Michael D. Dickey & Zhen Gu, 2015. "Transformable liquid-metal nanomedicine," Nature Communications, Nature, vol. 6(1), pages 1-10, December.
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