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Pharmacological and Nonpharmacological Treatments for Cardiac Hypertrophy

Author

Listed:
  • Rodrigo MS
  • Thássio RRM

    (Department of Physiology, Federal University of Sergipe, Brazil)

Abstract

Cardiac hypertrophy is an adaptive response of the heart to a large variety of extrinsic and intrinsic stimuli, including maladaptive remodeling in response to pathological conditions or to a physiological stimulus such as exercise training. In spite of the cardiac remodeling, classical features differ the pathological and physiological cardiac hypertrophy, in which the pathological remodeling has been associated with several cardiovascular diseases such as heart failure, a major cause of morbidity and mortality. However, there is still no consensus regarding therapies for the treatment of cardiac hypertrophy. In line with the imperative need for new strategies for its treatment, this review is focused on the importance of cholinergic signaling regulation by conventional and alternative drug therapies as well as in the beneficial contribution of exercise as a nonpharmacological approach.

Suggested Citation

  • Rodrigo MS & Thássio RRM, 2017. "Pharmacological and Nonpharmacological Treatments for Cardiac Hypertrophy," Global Journal of Pharmacy & Pharmaceutical Sciences, Juniper Publishers Inc., vol. 2(3), pages 59-62, May.
    • Handle: RePEc:adp:jgjpps:v:2:y:2017:i:3:p:59-62
    DOI: 10.19080/GJPPS.2017.02.555587
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