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Can Ovarian Auto Transplantation Become a Reasonable Alternative to Treat Symptomatic Menopause?

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  • BM Petrikovsky

    (Professor and former Chair of Obstetrics & Gynecology, Nassau University Medical Center, USA)

Abstract

Collaborative group on Hormonal Factors in Breast Cancer recently published their meta- analysis study linking hormonal replacement (HR) to breast cancer [1]. These authors concluded that HR users are at greater risk of invasive breast cancer compared to non-HR users. Risks are greater for current users, but some degree of risk persisted for more than a decade after HR use ceased. Breast cancer risks did not differ whether estrogens were administered orally or transdermally [1]. There appeared to be little risk from topical vaginal preparations [1]. The collaborative study included 143887 postmenopausal women on HR therapy (study group) and 424972 without HR therapy (controls). The study reported an increase breast cancer incidence by about one in every 50 users of estrogen plus daily progestogen; one in every 70 users of estrogen plus intermittent progestogen and one in every 200 users of estrogen only preparations.

Suggested Citation

  • BM Petrikovsky, 2019. "Can Ovarian Auto Transplantation Become a Reasonable Alternative to Treat Symptomatic Menopause?," Global Journal of Reproductive Medicine, Juniper Publishers Inc., vol. 7(2), pages 37-392:7, November.
    • Handle: RePEc:adp:jgjorm:v:7:y:2019:i:2:p:37-39
    DOI: 10.19080/GJORM.2019.07.555708
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