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Use of Dexmedetomidine and Ketamine for Rapid Opioids Detoxification in General Anesthesia

Author

Listed:
  • Ali Jabbari

    (Assistant professor, Department of Anesthesiology and Intensive Care Medicine, Golestan University of Medical Sciences, Iran)

  • Ebrahim Alijanpour

    (Associated professor, Department of Anesthesiology and Critical Care Medicine, Babol University of Medical Sciences, Iran)

  • Vahid Khuri

    (Professor of Ischemic Disorders Research Center of Golestan University of Medical Sciences, Iran)

  • Alireza Jahangirifard

    (Associate professor, Shahid Beheshti University of Medical Sciences, Iran)

Abstract

Deliverance from opioids dependency is challenging subjects and there are varieties of methods. There are new approaches base on anesthesia techniques for rapid opioids’ detoxification and recently, these methods are increasingly popular. These methods aimed at reducing the time of opioid detoxification and decreasing intensity of opioids withdrawal. Our protocol for opiate detoxification under general anesthesia by using Propofol, Dexmedetomidine plus ketamine while patients receive Naloxone represents a potentially effective treatment, and it could constitute as a safe method. We found less hemodynamic changes, withdrawal signs like involuntary movement, muscle twitch, lacrimation and sweating comparison with a combination of Propofol, Midazolam, and Atracurium. We believe that a well- designed protocol will accelerate detoxification and attenuate withdrawal symptoms.

Suggested Citation

  • Ali Jabbari & Ebrahim Alijanpour & Vahid Khuri & Alireza Jahangirifard, 2019. "Use of Dexmedetomidine and Ketamine for Rapid Opioids Detoxification in General Anesthesia," Global Journal of Addiction & Rehabilitation Medicine, Juniper Publishers Inc., vol. 6(3), pages 46-48, March.
    • Handle: RePEc:adp:jgjarm:v:6:y:2019:i:3:p:46-48
    DOI: 10.19080/GJARM.2019.06.555690
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