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Metformin and Prostate Cancer: A New Era of Prostate Cancer Research

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  • Bader A Abdelmaksoud

    (Department of clinical oncology and nuclear medicine, Zagazig University, Egypt)

Abstract

Metformin, a biguanide, is primary used in the treatment of type 2 diabetes mellitus (T2DM). Recently, there is a growing interest to examine its role in treatment of different types of cancers [1]. Franciosi and colleagues found a reduction in the risk of development of any cancer due to Metformin use in individuals with T2DM in their systematic review; also, other three systematic reviews assessed the effects of Metformin in individuals with any type of cancer. In meta-analysis of other 20 studies for individuals with T2DM showed that Metformin was associated with a 34% reduction in overall mortality and a 38% reduction in cancer-specific mortality.

Suggested Citation

  • Bader A Abdelmaksoud, 2018. "Metformin and Prostate Cancer: A New Era of Prostate Cancer Research," Cancer Therapy & Oncology International Journal, Juniper Publishers Inc., vol. 9(4), pages 133-134, March.
    • Handle: RePEc:adp:jctoij:v:9:y:2018:i:4:p:133-134
    DOI: 10.19080/CTOIJ.2018.09.555774
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