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Functional Recovery and Functional Magnetic Resonance Imaging changes Following Cellular Therapy in a Case of Chronic Complete Spinal Cord Injury

Author

Listed:
  • Alok Sharma
  • Nandini Gokulchandran

    (Department of Medical Services and Clinical research, Neuro Gen Brain & Spine Institute, India)

  • Suhasini Pai
  • Hemangi Sane
  • Samson Nivins
  • Pooja Kulkarni
  • Amruta Paranjape

    (Department of Research & Development, Neuro Gen Brain & Spine Institute, India)

  • Dhara Mehta

    (Department of Neuro rehabilitation, Neuro Gen Brain & Spine Institute, India)

  • Prerna Badhe

Abstract

Functional Magnetic Resonance Imaging (fMRI) is a non-invasive technique to monitor brain activity that provides detailed maps of the brain areas. A number of task-induced fMRI studies have demonstrated rearrangement of cortical activation patterns in the secondary brain areas in SCI patients. Chronic spinal cord injury (SCI) is a devastating disorder afflicting millions across the world. Cellular transplantation is one of the recent strategies to treat chronic complete SCI through its neuroregenerative and neurorestorative property. In this case we administered autologous bone marrow mononuclear cells intrathecally. The follow up assessment was conducted at three and seven months after the cellular therapy. Improvements in gross and fine motor activities, ambulation, bed mobilities, transfers, gait and bladder management were noted over a period of 7 months after the intervention.

Suggested Citation

  • Alok Sharma & Nandini Gokulchandran & Suhasini Pai & Hemangi Sane & Samson Nivins & Pooja Kulkarni & Amruta Paranjape & Dhara Mehta & Prerna Badhe, 2017. "Functional Recovery and Functional Magnetic Resonance Imaging changes Following Cellular Therapy in a Case of Chronic Complete Spinal Cord Injury," Current Trends in Clinical & Medical Imaging, Juniper Publishers Inc., vol. 1(4), pages 56-60, April.
    • Handle: RePEc:adp:jctcmi:v:1:y:2017:i:4:p:56-60
    DOI: 10.19080/CTCMI.2017.01.555566
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