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Is RBM20 a Promising Target for HFpEF Therapy?

Author

Listed:
  • Wei Guo
  • Andrea R Sanchez Walk

    (Animal Science, University of Wyoming, Laramie, USA
    Center for Cardiovascular Research and Integrative Medicine, University of Wyoming, USA,)

Abstract

Heart Failure (HF) is a major public health issue with an estimated prevalence of over 37.7 million individuals worldwide [1], and remains the leading cause of morbidity, mortality, and hospitalization among adults and elderly [2,3]. In the USA, the total medical costs for patients with HF are expected to rise from US$20.9 billion in 2012 to $53.1 billion by 2030 [1]. About half of the patients with heart failure display preserved ejection fraction in contrast to the other half that present contractile dysfunction and a dilated heart (HF with reduced ejection fraction, HFrEF) [4,5].

Suggested Citation

  • Wei Guo & Andrea R Sanchez Walk, 2017. "Is RBM20 a Promising Target for HFpEF Therapy?," Current Trends in Biomedical Engineering & Biosciences, Juniper Publishers Inc., vol. 3(5), pages 86-88, May.
  • Handle: RePEc:adp:jctbeb:v:3:y:2017:i:5:p:86-88
    DOI: 10.19080/CTBEB.2017.03.555625
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