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Feature Selection for Cancer Classification Using Microarray Gene Expression Data

Author

Listed:
  • Wenyan Zhong

    (Department of Mathematics and Statistics, University of Calgary, Canada)

  • Jingjing Wu

    (Department of Mathematics and Statistics, University of Calgary, Canada)

Abstract

The DNA microarray technology enables us to measure the expression levels of thousands of genes simultaneously, providing great chance for cancer diagnosis and prognosis. The number of genes often exceeds tens of thousands, whereas the number of subjects available is often no more than a hundred. Therefore, it is necessary and important to perform gene selection for classification purpose. A good subset of discriminative genes can improve prediction accuracy of classifiers and save computational cost with reduced dimension of data.

Suggested Citation

  • Wenyan Zhong & Jingjing Wu, 2017. "Feature Selection for Cancer Classification Using Microarray Gene Expression Data," Biostatistics and Biometrics Open Access Journal, Juniper Publishers Inc., vol. 1(2), pages 33-39, April.
  • Handle: RePEc:adp:jbboaj:v:1:y:2017:i:2:p:33-39
    DOI: 10.19080/BBOAJ.2017.01.555557
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    References listed on IDEAS

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    1. Shim, Jooyong & Sohn, Insuk & Kim, Sujong & Lee, Jae Won & Green, Paul E. & Hwang, Changha, 2009. "Selecting marker genes for cancer classification using supervised weighted kernel clustering and the support vector machine," Computational Statistics & Data Analysis, Elsevier, vol. 53(5), pages 1736-1742, March.
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