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The Genetic Multi-Variates-PTEN Hamartoma Tumour Syndrome

Author

Listed:
  • Anubha Bajaj

    (Department of Diagnostics, Punjab University, India)

Abstract

Phosphatase and tens in homologue as detected upon chromosome ten is enunciated as 10q23(PTEN). The PTEN gene usually encodes cytosolic lipid phosphatase composed of 403 amino acids which negatively regulates AKT (serine/threonine-specific protein kinase) activity by delineating dephosphorylating phosphatidylinositol 3,4,5, -trisphosphate (PIP3) molecule. A secretory form of PTEN is exemplified as PTEN-long or PTEN- L with the incorporation of an excess of 173 amino acid which adheres to the N- terminal of PTEN.

Suggested Citation

  • Anubha Bajaj, 2019. "The Genetic Multi-Variates-PTEN Hamartoma Tumour Syndrome," International Journal of Cell Science & Molecular Biology, Juniper Publishers Inc., vol. 6(3), pages 99-105, October.
    • Handle: RePEc:adp:ijcsmb:v:6:y:2019:i:3:p:99-105
    DOI: 10.19080/IJCSMB.2019.06.555692
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