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Synthesis and Photophysical Characterization of a Photoaffinity Molecular Switch

Author

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  • Shude Pang
  • Yingying Shi
  • Yanru Zhang

Abstract

In recent years, the development of some photoswitches based on azobenzene group provides a good tool for high spatio-temporal and precise regulation of ion channels and protein receports, but these small molecular photoswitches are very easily diffused in organisms. To overcome this limit, we have designed a photoswitches SY1 containing photocrosslinked group diazirine. The photoswitch was synthesized by the condensation reaction between azobenzene derivative and diazirine. The structure of the compound was characterized by 1H NMR and HR-MS, and the photophysical properties of the photoswtich SY1 were studied by UV-vis spectroscopy in different solvent systems. The results show that SY1 has excellent photodependent isomerization.

Suggested Citation

  • Shude Pang & Yingying Shi & Yanru Zhang, 2023. "Synthesis and Photophysical Characterization of a Photoaffinity Molecular Switch," International Journal of Sciences, Office ijSciences, vol. 12(08), pages 28-31, August.
    • Handle: RePEc:adm:journl:v:12:y:2023:i:8:p:28-31
    DOI: 10.18483/ijSci.2715
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