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Costs of Inflammatory Bowel Disease in Germany

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  • Renee Stark
  • Hans-Helmut König
  • Reiner Leidl

Abstract

Introduction: Inflammatory bowel disease (IBD) is a chronic condition that afflicts young adults in their economically productive years. The goal of this study was to determine the costs of IBD in Germany from a societal perspective, using cost diaries. Methods: Members of the German Crohn’s Disease and Ulcerative Colitis Association who had IBD were recruited by post, and those who agreed to participate documented their IBD-associated costs prospectively in a diary over 4 weeks. They documented their use of healthcare facilities, medications, sick leave and out-of-pocket expenditures, as well as general demographic information, the status and history of their IBD, and long-term disability. Item costs were calculated according to national sources. Cost data were calculated using non-parametric bootstrapping and presented as mean costs (year 2004) over 4 weeks. Results: The cost diaries were returned by 483 subjects (Crohn’s disease: n=241, ulcerative colitis: n=242) with a mean age of 42 years and an average disease duration of 13 years (SD ± 8.09). The cost diaries were regarded as ‘easy to complete’ by 89% of participants. The mean 4-week costs per subject were €1425 (95% CI 1201, 1689) for Crohn’s disease and €1015 (95% CI 832, 1258) for ulcerative colitis. Of the total costs for Crohn’s disease, 64% were due to indirect costs such as early retirement or sick leave and 32% were due to direct medical costs. In contrast, of the total costs for ulcerative colitis, 41% were due to direct medical costs and 54% to indirect costs. Conclusions: This is the first comprehensive cost study for Crohn’s disease and ulcerative colitis in Germany. The most important economic factors that influenced the cost profiles of both diseases were the long-term productivity losses due to an ongoing inability to work and the cost of medications. Results indicate significant cost differences between Crohn’s disease and ulcerative colitis. This data provides initial cost estimates that can be analysed further with respect to cost determinants and disease-specific costs in the future. Copyright Adis Data Information BV 2006

Suggested Citation

  • Renee Stark & Hans-Helmut König & Reiner Leidl, 2006. "Costs of Inflammatory Bowel Disease in Germany," PharmacoEconomics, Springer, vol. 24(8), pages 797-814, August.
  • Handle: RePEc:spr:pharme:v:24:y:2006:i:8:p:797-814
    DOI: 10.2165/00019053-200624080-00006
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    Citations

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    Cited by:

    1. Andersen, Signe Hald, 2010. "The cost of sickness: On the effect of the duration of sick leave on post-sick leave earnings," Social Science & Medicine, Elsevier, vol. 70(10), pages 1581-1589, May.
    2. Mirthe E van der Valk & Marie-Josée J Mangen & Mirjam Severs & Mike van der Have & Gerard Dijkstra & Ad A van Bodegraven & Herma H Fidder & Dirk J de Jong & C Janneke van der Woude & Mariëlle J L Romb, 2016. "Evolution of Costs of Inflammatory Bowel Disease over Two Years of Follow-Up," PLOS ONE, Public Library of Science, vol. 11(4), pages 1-11, April.
    3. Marina Kostić & Ljiljan Djakovic & Raša Šujić & Brian Godman & Slobodan M. Janković, 2017. "Inflammatory Bowel Diseases (Crohn´s Disease and Ulcerative Colitis): Cost of Treatment in Serbia and the Implications," Applied Health Economics and Health Policy, Springer, vol. 15(1), pages 85-93, February.
    4. Przemysław Holko & Paweł Kawalec & Magdalena Sajak-Szczerba & Luisa Avedano & Małgorzata Mossakowska, 2023. "Out-of-pocket expenses of patients with inflammatory bowel disease: a comparison of patient-reported outcomes across 12 European countries," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 24(7), pages 1073-1083, September.
    5. Przemysław Holko & Paweł Kawalec & Małgorzata Mossakowska & Andrzej Pilc, 2016. "Health-Related Quality of Life Impairment and Indirect Cost of Crohn’s Disease: A Self-Report Study in Poland," PLOS ONE, Public Library of Science, vol. 11(12), pages 1-21, December.
    6. Renata S. B. Fróes & Ana Teresa Pugas Carvalho & Antonio Jose V. Carneiro & Adriana Maria Hilu Barros Moreira & Jessica P. L. Moreira & Ronir R. Luiz & Heitor S. de Souza, 2018. "The socio-economic impact of work disability due to inflammatory bowel disease in Brazil," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 19(3), pages 463-470, April.
    7. Anne Prenzler & Bernd Bokemeyer & J.-Matthias Schulenburg & Thomas Mittendorf, 2011. "Health care costs and their predictors of inflammatory bowel diseases in Germany," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 12(3), pages 273-283, June.

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