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QALYs for COVID-19: A Comparison of US EQ-5D-5L Value Sets

Author

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  • Stephen Poteet

    (St. Petersburg College)

  • Benjamin M. Craig

    (University of South Florida)

Abstract

Background In economic evaluations, quality-adjusted life-years (QALYs) can serve as a unit of measurement for disease burden. Obtaining QALY values for COVID-19 presents a challenge owing to the availability of two US EQ-5D-5L value sets and the potentially asymptomatic presentation of the disease. The first value set was completed allowing for the discounting of future health outcomes while the second value set is undiscounted. Objective The objective of this study was to compare the distribution of QALY values using a national survey and the two published value sets; and to estimate the association between COVID-19 outcomes and QALY losses. Methods Between 9 and 11 November, 2020, 1153 US adults completed the EQ-5D-5L instrument (five items and a visual analog scale) as well as self-reported their demographics, COVID-19 symptoms, and memberships to populations that are at risk of COVID-19 infection. The two US value sets were applied to the EQ-5D-5L responses to produce QALY values. We estimated the mean QALYs by visual analog scale decile and a generalized linear model of COVID-19 outcomes. Results The discounted values are higher than the undiscounted values for each visual analog scale decile owing to methodological differences. Persons at increased risk, with a fever in the past day, and with one or more other symptoms have significantly greater QALY losses (p

Suggested Citation

  • Stephen Poteet & Benjamin M. Craig, 2021. "QALYs for COVID-19: A Comparison of US EQ-5D-5L Value Sets," The Patient: Patient-Centered Outcomes Research, Springer;International Academy of Health Preference Research, vol. 14(3), pages 339-345, May.
    • Handle: RePEc:spr:patien:v:14:y:2021:i:3:d:10.1007_s40271-021-00509-z
    DOI: 10.1007/s40271-021-00509-z
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    References listed on IDEAS

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    1. Nancy J. Devlin & Richard Brooks, 2017. "EQ-5D and the EuroQol Group: Past, Present and Future," Applied Health Economics and Health Policy, Springer, vol. 15(2), pages 127-137, April.
    2. Jones, A.M, 2010. "Models For Health Care," Health, Econometrics and Data Group (HEDG) Working Papers 10/01, HEDG, c/o Department of Economics, University of York.
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    1. Erin Kirwin & Ellen Rafferty & Kate Harback & Jeff Round & Christopher McCabe, 2021. "A Net Benefit Approach for the Optimal Allocation of a COVID-19 Vaccine," PharmacoEconomics, Springer, vol. 39(9), pages 1059-1073, September.
    2. Rachael L. DiSantostefano & Fern Terris-Prestholt, 2021. "Using Societal Values to Inform Public Health Policy During the COVID-19 Pandemic: The Role of Health Preference Research," The Patient: Patient-Centered Outcomes Research, Springer;International Academy of Health Preference Research, vol. 14(3), pages 303-307, May.

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