Content
April 2017, Volume 8, Issue 1
- 1-13 Chiral acidic amino acids induce chiral hierarchical structure in calcium carbonate
by Wenge Jiang & Michael S. Pacella & Dimitra Athanasiadou & Valentin Nelea & Hojatollah Vali & Robert M. Hazen & Jeffrey J. Gray & Marc D. McKee - 1-13 Gα13 negatively controls osteoclastogenesis through inhibition of the Akt-GSK3β-NFATc1 signalling pathway
by Mengrui Wu & Wei Chen & Yun Lu & Guochun Zhu & Liang Hao & Yi-Ping Li - 1-13 Deconvolution of Buparlisib’s mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention
by Thomas Bohnacker & Andrea E. Prota & Florent Beaufils & John E. Burke & Anna Melone & Alison J. Inglis & Denise Rageot & Alexander M. Sele & Vladimir Cmiljanovic & Natasa Cmiljanovic & Katja Bargsten & Amol Aher & Anna Akhmanova & J. Fernando Díaz & Doriano Fabbro & Marketa Zvelebil & Roger L. Williams & Michel O. Steinmetz & Matthias P. Wymann - 1-13 Glutaredoxin catalysis requires two distinct glutathione interaction sites
by Patricia Begas & Linda Liedgens & Anna Moseler & Andreas J. Meyer & Marcel Deponte - 1-13 Dendritic cell MST1 inhibits Th17 differentiation
by Chunxiao Li & Yujing Bi & Yan Li & Hui Yang & Qing Yu & Jian Wang & Yu Wang & Huilin Su & Anna Jia & Ying Hu & Linian Han & Jiangyuan Zhang & Simin Li & Wufan Tao & Guangwei Liu - 1-13 Innovation and constraint leading to complex multicellularity in the Ascomycota
by Tu Anh Nguyen & Ousmane H. Cissé & Jie Yun Wong & Peng Zheng & David Hewitt & Minou Nowrousian & Jason E. Stajich & Gregory Jedd - 1-13 Monocytic and granulocytic myeloid derived suppressor cells differentially regulate spatiotemporal tumour plasticity during metastatic cascade
by Maria Ouzounova & Eunmi Lee & Raziye Piranlioglu & Abdeljabar El Andaloussi & Ravindra Kolhe & Mehmet F. Demirci & Daniela Marasco & Iskander Asm & Ahmed Chadli & Khaled A. Hassan & Muthusamy Thangaraju & Gang Zhou & Ali S. Arbab & John K. Cowell & Hasan Korkaya - 1-13 A human immunodeficiency syndrome caused by mutations in CARMIL2
by T. Schober & T. Magg & M. Laschinger & M. Rohlfs & N. D. Linhares & J. Puchalka & T. Weisser & K. Fehlner & J. Mautner & C. Walz & K. Hussein & G. Jaeger & B. Kammer & I. Schmid & M. Bahia & S. D. Pena & U. Behrends & B. H. Belohradsky & C. Klein & F. Hauck - 1-13 CD40-signalling abrogates induction of RORγt+ Treg cells by intestinal CD103+ DCs and causes fatal colitis
by Christian Barthels & Ana Ogrinc & Verena Steyer & Stefanie Meier & Ferdinand Simon & Maria Wimmer & Andreas Blutke & Tobias Straub & Ursula Zimber-Strobl & Esther Lutgens & Peggy Marconi & Caspar Ohnmacht & Debora Garzetti & Bärbel Stecher & Thomas Brocker - 1-13 Polymeric mechanical amplifiers of immune cytokine-mediated apoptosis
by Michael J. Mitchell & Jamie Webster & Amanda Chung & Pedro P. G. Guimarães & Omar F. Khan & Robert Langer - 1-13 The human amygdala parametrically encodes the intensity of specific facial emotions and their categorical ambiguity
by Shuo Wang & Rongjun Yu & J. Michael Tyszka & Shanshan Zhen & Christopher Kovach & Sai Sun & Yi Huang & Rene Hurlemann & Ian B. Ross & Jeffrey M. Chung & Adam N. Mamelak & Ralph Adolphs & Ueli Rutishauser - 1-13 Lateral orbitofrontal cortex anticipates choices and integrates prior with current information
by Ramon Nogueira & Juan M. Abolafia & Jan Drugowitsch & Emili Balaguer-Ballester & Maria V. Sanchez-Vives & Rubén Moreno-Bote - 1-13 Chromatin remodeller Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation
by Junwoo Lee & Eun Shik Choi & Hogyu David Seo & Keunsoo Kang & Joshua M. Gilmore & Laurence Florens & Michael P. Washburn & Joonho Choe & Jerry L. Workman & Daeyoup Lee - 1-13 Saturated palmitic acid induces myocardial inflammatory injuries through direct binding to TLR4 accessory protein MD2
by Yi Wang & Yuanyuan Qian & Qilu Fang & Peng Zhong & Weixin Li & Lintao Wang & Weitao Fu & Yali Zhang & Zheng Xu & Xiaokun Li & Guang Liang - 1-13 Cellular mechano-environment regulates the mammary circadian clock
by Nan Yang & Jack Williams & Vanja Pekovic-Vaughan & Pengbo Wang & Safiah Olabi & James McConnell & Nicole Gossan & Alun Hughes & Julia Cheung & Charles H. Streuli & Qing-Jun Meng - 1-13 Reconstruction of the metabolic network of Pseudomonas aeruginosa to interrogate virulence factor synthesis
by Jennifer A. Bartell & Anna S. Blazier & Phillip Yen & Juliane C. Thøgersen & Lars Jelsbak & Joanna B. Goldberg & Jason A. Papin - 1-13 STIM1 activates CRAC channels through rotation of the pore helix to open a hydrophobic gate
by Megumi Yamashita & Priscilla S.-W. Yeung & Christopher E. Ing & Beth A. McNally & Régis Pomès & Murali Prakriya - 1-13 Human seizures couple across spatial scales through travelling wave dynamics
by L-E Martinet & G. Fiddyment & J. R. Madsen & E. N. Eskandar & W. Truccolo & U. T. Eden & S. S. Cash & M. A. Kramer - 1-13 Identification of common non-coding variants at 1p22 that are functional for non-syndromic orofacial clefting
by Huan Liu & Elizabeth J. Leslie & Jenna C. Carlson & Terri H. Beaty & Mary L. Marazita & Andrew C. Lidral & Robert A. Cornell - 1-13 Regioregular narrow-bandgap-conjugated polymers for plastic electronics
by Lei Ying & Fei Huang & Guillermo C. Bazan - 1-13 SMARCA4-inactivating mutations increase sensitivity to Aurora kinase A inhibitor VX-680 in non-small cell lung cancers
by Vural Tagal & Shuguang Wei & Wei Zhang & Rolf A. Brekken & Bruce A. Posner & Michael Peyton & Luc Girard & TaeHyun Hwang & David A. Wheeler & John D. Minna & Michael A. White & Adi F. Gazdar & Michael G. Roth - 1-13 Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus
by Takafumi Suzuki & Shiori Seki & Keiichiro Hiramoto & Eriko Naganuma & Eri H. Kobayashi & Ayaka Yamaoka & Liam Baird & Nobuyuki Takahashi & Hiroshi Sato & Masayuki Yamamoto - 1-13 Massive production of abiotic methane during subduction evidenced in metamorphosed ophicarbonates from the Italian Alps
by Alberto Vitale Brovarone & Isabelle Martinez & Agnès Elmaleh & Roberto Compagnoni & Carine Chaduteau & Cristiano Ferraris & Imène Esteve - 1-13 A retinoraphe projection regulates serotonergic activity and looming-evoked defensive behaviour
by Lu Huang & Tifei Yuan & Minjie Tan & Yue Xi & Yu Hu & Qian Tao & Zhikai Zhao & Jiajun Zheng & Yushui Han & Fuqiang Xu & Minmin Luo & Patricia J. Sollars & Mingliang Pu & Gary E. Pickard & Kwok-Fai So & Chaoran Ren - 1-13 Cell fate decisions emerge as phages cooperate or compete inside their host
by Jimmy T. Trinh & Tamás Székely & Qiuyan Shao & Gábor Balázsi & Lanying Zeng - 1-13 The tumour suppressor APC promotes HIV-1 assembly via interaction with Gag precursor protein
by Kei Miyakawa & Mayuko Nishi & Satoko Matsunaga & Akiko Okayama & Masaki Anraku & Ayumi Kudoh & Hisashi Hirano & Hirokazu Kimura & Yuko Morikawa & Naoki Yamamoto & Akira Ono & Akihide Ryo - 1-13 Enhancing titres of therapeutic viral vectors using the transgene repression in vector production (TRiP) system
by H. E. Maunder & J. Wright & B. R. Kolli & C. R. Vieira & T. T. Mkandawire & S. Tatoris & V. Kennedy & S. Iqball & G. Devarajan & S. Ellis & Y. Lad & N. G. Clarkson & K. A. Mitrophanous & D. C. Farley - 1-13 Major sulfonate transporter Soa1 in Saccharomyces cerevisiae and considerable substrate diversity in its fungal family
by Sylvester Holt & Harish Kankipati & Stijn De Graeve & Griet Van Zeebroeck & Maria R. Foulquié-Moreno & Stinus Lindgreen & Johan M. Thevelein - 1-13 Experimental evidence for circular inference in schizophrenia
by Renaud Jardri & Sandrine Duverne & Alexandra S Litvinova & Sophie Denève - 1-13 Evidence for ACTN3 as a genetic modifier of Duchenne muscular dystrophy
by Marshall W. Hogarth & Peter J. Houweling & Kristen C. Thomas & Heather Gordish-Dressman & Luca Bello & Elena Pegoraro & Eric P. Hoffman & Stewart I. Head & Kathryn N. North - 1-13 Small-molecule-biased formyl peptide receptor agonist compound 17b protects against myocardial ischaemia-reperfusion injury in mice
by Cheng Xue Qin & Lauren T. May & Renming Li & Nga Cao & Sarah Rosli & Minh Deo & Amy E. Alexander & Duncan Horlock & Jane E. Bourke & Yuan H. Yang & Alastair G. Stewart & David M. Kaye & Xiao-Jun Du & Patrick M. Sexton & Arthur Christopoulos & Xiao-Ming Gao & Rebecca H. Ritchie - 1-13 Photothermally triggered actuation of hybrid materials as a new platform for in vitro cell manipulation
by Amy Sutton & Tanya Shirman & Jaakko V. I. Timonen & Grant T England & Philseok Kim & Mathias Kolle & Thomas Ferrante & Lauren D Zarzar & Elizabeth Strong & Joanna Aizenberg - 1-13 A microRNA-initiated DNAzyme motor operating in living cells
by Hanyong Peng & Xing-Fang Li & Hongquan Zhang & X. Chris Le - 1-13 Adipocytes promote malignant growth of breast tumours with monocarboxylate transporter 2 expression via β-hydroxybutyrate
by Chun-Kai Huang & Po-Hao Chang & Wen-Hung Kuo & Chi-Long Chen & Yung-Ming Jeng & King-Jen Chang & Jin-Yuh Shew & Chun-Mei Hu & Wen-Hwa Lee - 1-13 IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting
by Kazuyoshi Takeda & Masafumi Nakayama & Yoshihiro Hayakawa & Yuko Kojima & Hiroaki Ikeda & Naoko Imai & Kouetsu Ogasawara & Ko Okumura & David M. Thomas & Mark J. Smyth - 1-13 Dysfunction of ventrolateral striatal dopamine receptor type 2-expressing medium spiny neurons impairs instrumental motivation
by Iku Tsutsui-Kimura & Hiroyuki Takiue & Keitaro Yoshida & Ming Xu & Ryutaro Yano & Hiroyuki Ohta & Hiroshi Nishida & Youcef Bouchekioua & Hideyuki Okano & Motokazu Uchigashima & Masahiko Watanabe & Norio Takata & Michael R. Drew & Hiromi Sano & Masaru Mimura & Kenji F. Tanaka - 1-13 Activin A more prominently regulates muscle mass in primates than does GDF8
by Esther Latres & Jason Mastaitis & Wen Fury & Lawrence Miloscio & Jesus Trejos & Jeffrey Pangilinan & Haruka Okamoto & Katie Cavino & Erqian Na & Angelos Papatheodorou & Tobias Willer & Yu Bai & Jee Hae Kim & Ashique Rafique & Stephen Jaspers & Trevor Stitt & Andrew J. Murphy & George D. Yancopoulos & Jesper Gromada - 1-13 Protein disulfide isomerase secretion following vascular injury initiates a regulatory pathway for thrombus formation
by Sheryl R. Bowley & Chao Fang & Glenn Merrill-Skoloff & Barbara C. Furie & Bruce Furie - 1-13 A mast cell-ILC2-Th9 pathway promotes lung inflammation in cystic fibrosis
by Silvia Moretti & Giorgia Renga & Vasilis Oikonomou & Claudia Galosi & Marilena Pariano & Rossana G. Iannitti & Monica Borghi & Matteo Puccetti & Marco De Zuani & Carlo E. Pucillo & Giuseppe Paolicelli & Teresa Zelante & Jean-Christophe Renauld & Oxana Bereshchenko & Paolo Sportoletti & Vincenzina Lucidi & Maria Chiara Russo & Carla Colombo & Ersilia Fiscarelli & Cornelia Lass-Flörl & Fabio Majo & Gabriella Ricciotti & Helmut Ellemunter & Luigi Ratclif & Vincenzo Nicola Talesa & Valerio Napolioni & Luigina Romani - 1-13 The immunoreceptor NKG2D promotes tumour growth in a model of hepatocellular carcinoma
by Sam Sheppard & Joana Guedes & Anna Mroz & Anastasia-Maria Zavitsanou & Hiromi Kudo & Stephen M. Rothery & Panagiotis Angelopoulos & Robert Goldin & Nadia Guerra - 1-13 Hotspots of aberrant enhancer activity punctuate the colorectal cancer epigenome
by Andrea J. Cohen & Alina Saiakhova & Olivia Corradin & Jennifer M. Luppino & Katreya Lovrenert & Cynthia F. Bartels & James J. Morrow & Stephen C. Mack & Gursimran Dhillon & Lydia Beard & Lois Myeroff & Matthew F. Kalady & Joseph Willis & James E. Bradner & Ruth A. Keri & Nathan A. Berger & Shondra M. Pruett-Miller & Sanford D. Markowitz & Peter C. Scacheri - 1-13 Demonstration of qubit operations below a rigorous fault tolerance threshold with gate set tomography
by Robin Blume-Kohout & John King Gamble & Erik Nielsen & Kenneth Rudinger & Jonathan Mizrahi & Kevin Fortier & Peter Maunz - 1-13 Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement
by Nikaïa Smith & Nicolas Pietrancosta & Sophia Davidson & Jacques Dutrieux & Lise Chauveau & Pasquale Cutolo & Michel Dy & Daniel Scott-Algara & Bénédicte Manoury & Onofrio Zirafi & Isabelle McCort-Tranchepain & Thierry Durroux & Françoise Bachelerie & Olivier Schwartz & Jan Münch & Andreas Wack & Sébastien Nisole & Jean-Philippe Herbeuval - 1-13 A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle
by Shuo Xiao & Jonathan R. Coppeta & Hunter B. Rogers & Brett C. Isenberg & Jie Zhu & Susan A. Olalekan & Kelly E. McKinnon & Danijela Dokic & Alexandra S. Rashedi & Daniel J. Haisenleder & Saurabh S. Malpani & Chanel A. Arnold-Murray & Kuanwei Chen & Mingyang Jiang & Lu Bai & Catherine T. Nguyen & Jiyang Zhang & Monica M. Laronda & Thomas J. Hope & Kruti P. Maniar & Mary Ellen Pavone & Michael J. Avram & Elizabeth C. Sefton & Spiro Getsios & Joanna E. Burdette & J. Julie Kim & Jeffrey T. Borenstein & Teresa K. Woodruff - 1-13 Diverse feather shape evolution enabled by coupling anisotropic signalling modules with self-organizing branching programme
by Ang Li & Seth Figueroa & Ting-Xin Jiang & Ping Wu & Randall Widelitz & Qing Nie & Cheng-Ming Chuong - 1-13 Infection-derived lipids elicit an immune deficiency circuit in arthropods
by Dana K. Shaw & Xiaowei Wang & Lindsey J. Brown & Adela S. Oliva Chávez & Kathryn E. Reif & Alexis A. Smith & Alison J. Scott & Erin E. McClure & Vishant M. Boradia & Holly L. Hammond & Eric J. Sundberg & Greg A. Snyder & Lei Liu & Kathleen DePonte & Margarita Villar & Massaro W. Ueti & José de la Fuente & Robert K. Ernst & Utpal Pal & Erol Fikrig & Joao H. F. Pedra - 1-13 RD26 mediates crosstalk between drought and brassinosteroid signalling pathways
by Huaxun Ye & Sanzhen Liu & Buyun Tang & Jiani Chen & Zhouli Xie & Trevor M. Nolan & Hao Jiang & Hongqing Guo & Hung-Ying Lin & Lei Li & Yanqun Wang & Hongning Tong & Mingcai Zhang & Chengcai Chu & Zhaohu Li & Maneesha Aluru & Srinivas Aluru & Patrick S. Schnable & Yanhai Yin - 1-13 Jasmonate response decay and defense metabolite accumulation contributes to age-regulated dynamics of plant insect resistance
by Ying-Bo Mao & Yao-Qian Liu & Dian-Yang Chen & Fang-Yan Chen & Xin Fang & Gao-Jie Hong & Ling-Jian Wang & Jia-Wei Wang & Xiao-Ya Chen - 1-13 IL-15 sustains IL-7R-independent ILC2 and ILC3 development
by Michelle L. Robinette & Jennifer K. Bando & Wilbur Song & Tyler K. Ulland & Susan Gilfillan & Marco Colonna - 1-13 Snf1-related kinase improves cardiac mitochondrial efficiency and decreases mitochondrial uncoupling
by Amy K. Rines & Hsiang-Chun Chang & Rongxue Wu & Tatsuya Sato & Arineh Khechaduri & Hidemichi Kouzu & Jason Shapiro & Meng Shang & Michael A. Burke & Eltyeb Abdelwahid & Xinghang Jiang & Chunlei Chen & Tenley A. Rawlings & Gary D. Lopaschuk & Paul T. Schumacker & E. Dale Abel & Hossein Ardehali - 1-13 Learning from data to design functional materials without inversion symmetry
by Prasanna V. Balachandran & Joshua Young & Turab Lookman & James M. Rondinelli - 1-13 Quantitative 3D analysis of complex single border cell behaviors in coordinated collective cell migration
by Adam Cliffe & David P. Doupé & HsinHo Sung & Isaac Kok Hwee Lim & Kok Haur Ong & Li Cheng & Weimiao Yu - 1-13 Defined chromosome structure in the genome-reduced bacterium Mycoplasma pneumoniae
by Marie Trussart & Eva Yus & Sira Martinez & Davide Baù & Yuhei O. Tahara & Thomas Pengo & Michael Widjaja & Simon Kretschmer & Jim Swoger & Steven Djordjevic & Lynne Turnbull & Cynthia Whitchurch & Makoto Miyata & Marc A. Marti-Renom & Maria Lluch-Senar & Luís Serrano - 1-13 Small genomic insertions form enhancers that misregulate oncogenes
by Brian J. Abraham & Denes Hnisz & Abraham S. Weintraub & Nicholas Kwiatkowski & Charles H. Li & Zhaodong Li & Nina Weichert-Leahey & Sunniyat Rahman & Yu Liu & Julia Etchin & Benshang Li & Shuhong Shen & Tong Ihn Lee & Jinghui Zhang & A. Thomas Look & Marc R. Mansour & Richard A. Young - 1-13 Biomimetically inspired asymmetric total synthesis of (+)-19-dehydroxyl arisandilactone A
by Yi-Xin Han & Yan-Long Jiang & Yong Li & Hai-Xin Yu & Bing-Qi Tong & Zhe Niu & Shi-Jie Zhou & Song Liu & Yu Lan & Jia-Hua Chen & Zhen Yang - 1-13 CRISPR–Cas9-targeted fragmentation and selective sequencing enable massively parallel microsatellite analysis
by GiWon Shin & Susan M. Grimes & HoJoon Lee & Billy T. Lau & Li C. Xia & Hanlee P. Ji - 1-13 Layer-specific optogenetic activation of pyramidal neurons causes beta–gamma entrainment of neonatal networks
by Sebastian H Bitzenhofer & Joachim Ahlbeck & Amy Wolff & J. Simon Wiegert & Christine E. Gee & Thomas G. Oertner & Ileana L. Hanganu-Opatz - 1-13 Local self-uniformity in photonic networks
by Steven R. Sellers & Weining Man & Shervin Sahba & Marian Florescu - 1-13 Drosophila FIT is a protein-specific satiety hormone essential for feeding control
by Jinghan Sun & Chang Liu & Xiaobing Bai & Xiaoting Li & Jingyun Li & Zhiping Zhang & Yunpeng Zhang & Jing Guo & Yan Li - 1-13 Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells
by Jeffrey Y. W. Mak & Weijun Xu & Robert C. Reid & Alexandra J. Corbett & Bronwyn S. Meehan & Huimeng Wang & Zhenjun Chen & Jamie Rossjohn & James McCluskey & Ligong Liu & David P. Fairlie - 1-13 PNPLA1 has a crucial role in skin barrier function by directing acylceramide biosynthesis
by Tetsuya Hirabayashi & Tatsuki Anjo & Arisa Kaneko & Yuuya Senoo & Akitaka Shibata & Hiroyuki Takama & Kohei Yokoyama & Yasumasa Nishito & Tomio Ono & Choji Taya & Kazuaki Muramatsu & Kiyoko Fukami & Agustí Muñoz-Garcia & Alan R. Brash & Kazutaka Ikeda & Makoto Arita & Masashi Akiyama & Makoto Murakami - 1-13 Dynamic transcriptomes identify biogenic amines and insect-like hormonal regulation for mediating reproduction in Schistosoma japonicum
by Jipeng Wang & Ying Yu & Haimo Shen & Tao Qing & Yuanting Zheng & Qing Li & Xiaojin Mo & Shuqi Wang & Nana Li & Riyi Chai & Bin Xu & Mu Liu & Paul J Brindley & Donald P McManus & Zheng Feng & Leming Shi & Wei Hu - 1-13 Disruption of cardiac cholinergic neurons enhances susceptibility to ventricular arrhythmias
by Christiane Jungen & Katharina Scherschel & Christian Eickholt & Pawel Kuklik & Niklas Klatt & Nadja Bork & Tim Salzbrunn & Fares Alken & Stephan Angendohr & Christiane Klene & Janos Mester & Nikolaj Klöcker & Marieke W. Veldkamp & Udo Schumacher & Stephan Willems & Viacheslav O. Nikolaev & Christian Meyer - 1-13 Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2
by Nuria Cerdá-Esteban & Heike Naumann & Silvia Ruzittu & Nancy Mah & Igor M. Pongrac & Corinna Cozzitorto & Angela Hommel & Miguel A. Andrade-Navarro & Ezio Bonifacio & Francesca M. Spagnoli - 1-13 DEK-targeting DNA aptamers as therapeutics for inflammatory arthritis
by Nirit Mor-Vaknin & Anjan Saha & Maureen Legendre & Carmelo Carmona-Rivera & M Asif Amin & Bradley J. Rabquer & Marta J. Gonzales-Hernandez & Julie Jorns & Smriti Mohan & Srilakshmi Yalavarthi & Dave A. Pai & Kristine Angevine & Shelley J. Almburg & Jason S. Knight & Barbara S. Adams & Alisa E. Koch & David A. Fox & David R. Engelke & Mariana J. Kaplan & David M. Markovitz - 1-13 The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction
by Kazuhiko Yamamura & Takehito Uruno & Akira Shiraishi & Yoshihiko Tanaka & Miho Ushijima & Takeshi Nakahara & Mayuki Watanabe & Makiko Kido-Nakahara & Ikuya Tsuge & Masutaka Furue & Yoshinori Fukui - 1-13 Theory of optimal balance predicts and explains the amplitude and decay time of synaptic inhibition
by Jaekyung K. Kim & Christopher D. Fiorillo - 1-13 Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects
by Mark Lucanic & W. Todd Plummer & Esteban Chen & Jailynn Harke & Anna C. Foulger & Brian Onken & Anna L. Coleman-Hulbert & Kathleen J. Dumas & Suzhen Guo & Erik Johnson & Dipa Bhaumik & Jian Xue & Anna B. Crist & Michael P. Presley & Girish Harinath & Christine A. Sedore & Manish Chamoli & Shaunak Kamat & Michelle K. Chen & Suzanne Angeli & Christina Chang & John H. Willis & Daniel Edgar & Mary Anne Royal & Elizabeth A. Chao & Shobhna Patel & Theo Garrett & Carolina Ibanez-Ventoso & June Hope & Jason L Kish & Max Guo & Gordon J. Lithgow & Monica Driscoll & Patrick C. Phillips - 1-13 EcR recruits dMi-2 and increases efficiency of dMi-2-mediated remodelling to constrain transcription of hormone-regulated genes
by Judith Kreher & Kristina Kovač & Karim Bouazoune & Igor Mačinković & Anna Luise Ernst & Erik Engelen & Roman Pahl & Florian Finkernagel & Magdalena Murawska & Ikram Ullah & Alexander Brehm - 1-13 Natural variation in CTB4a enhances rice adaptation to cold habitats
by Zhanying Zhang & Jinjie Li & Yinghua Pan & Jilong Li & Lei zhou & Hongli Shi & Yawen Zeng & Haifeng Guo & Shuming Yang & Weiwei Zheng & Jianping Yu & Xingming Sun & Gangling Li & Yanglin Ding & Liang Ma & Shiquan Shen & Luyuan Dai & Hongliang Zhang & Shuhua Yang & Yan Guo & Zichao Li - 1-13 Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells
by Pietro Giuseppe Mazzara & Luca Massimino & Marta Pellegatta & Giulia Ronchi & Alessandra Ricca & Angelo Iannielli & Serena Gea Giannelli & Marco Cursi & Cinzia Cancellieri & Alessandro Sessa & Ubaldo Del Carro & Angelo Quattrini & Stefano Geuna & Angela Gritti & Carla Taveggia & Vania Broccoli - 1-13 Infrared laser-induced gene expression for tracking development and function of single C. elegans embryonic neurons
by Anupriya Singhal & Shai Shaham - 1-13 Cell-size dependent progression of the cell cycle creates homeostasis and flexibility of plant cell size
by Angharad R. Jones & Manuel Forero-Vargas & Simon P. Withers & Richard S. Smith & Jan Traas & Walter Dewitte & James A. H. Murray - 1-13 Regional cooling caused recent New Zealand glacier advances in a period of global warming
by Andrew N. Mackintosh & Brian M. Anderson & Andrew M. Lorrey & James A. Renwick & Prisco Frei & Sam M. Dean - 1-13 Fluorene-9-bisphenol is anti-oestrogenic and may cause adverse pregnancy outcomes in mice
by Zhaobin Zhang & Ying Hu & Jilong Guo & Tong Yu & Libei Sun & Xuan Xiao & Desheng Zhu & Tsuyoshi Nakanishi & Youhei Hiromori & Junyu Li & Xiaolin Fan & Yi Wan & Siyu Cheng & Jun Li & Xuan Guo & Jianying Hu - 1-13 The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger
by Maria-Cristina Keightley & Duncan P. Carradice & Judith E. Layton & Luke Pase & Julien Y. Bertrand & Johannes G. Wittig & Aleksandar Dakic & Andrew P. Badrock & Nicholas J. Cole & David Traver & Stephen L. Nutt & Julia McCoey & Ashley M. Buckle & Joan K. Heath & Graham J. Lieschke - 1-13 Conformational changes in intact dengue virus reveal serotype-specific expansion
by Xin-Xiang Lim & Arun Chandramohan & Xin Ying Elisa Lim & Nirmalya Bag & Kamal Kant Sharma & Melissa Wirawan & Thorsten Wohland & Shee-Mei Lok & Ganesh S. Anand - 1-13 Recurrently deregulated lncRNAs in hepatocellular carcinoma
by Yang Yang & Lei Chen & Jin Gu & Hanshuo Zhang & Jiapei Yuan & Qiuyu Lian & Guishuai Lv & Siqi Wang & Yang Wu & Yu-Cheng T. Yang & Dongfang Wang & Yang Liu & Jing Tang & Guijuan Luo & Yang Li & Long Hu & Xinbao Sun & Dong Wang & Mingzhou Guo & Qiaoran Xi & Jianzhong Xi & Hongyang Wang & Michael Q. Zhang & Zhi John Lu - 1-13 Allosteric modulation of peroxisomal membrane protein recognition by farnesylation of the peroxisomal import receptor PEX19
by Leonidas Emmanouilidis & Ulrike Schütz & Konstantinos Tripsianes & Tobias Madl & Juliane Radke & Robert Rucktäschel & Matthias Wilmanns & Wolfgang Schliebs & Ralf Erdmann & Michael Sattler - 1-13 FAK signalling controls insulin sensitivity through regulation of adipocyte survival
by Cynthia T. Luk & Sally Yu Shi & Erica P. Cai & Tharini Sivasubramaniyam & Mansa Krishnamurthy & Jara J. Brunt & Stephanie A. Schroer & Daniel A. Winer & Minna Woo - 1-13 Distinct molecular cues ensure a robust microtubule-dependent nuclear positioning in the Drosophila oocyte
by Nicolas Tissot & Jean-Antoine Lepesant & Fred Bernard & Kevin Legent & Floris Bosveld & Charlotte Martin & Orestis Faklaris & Yohanns Bellaïche & Maïté Coppey & Antoine Guichet - 1-13 Structural and functional analysis of the human POT1-TPP1 telomeric complex
by Cory Rice & Prashanth Krishna Shastrula & Andrew V. Kossenkov & Robert Hills & Duncan M. Baird & Louise C. Showe & Tzanko Doukov & Susan Janicki & Emmanuel Skordalakes - 1-13 Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer
by Julienne L. Carstens & Pedro Correa de Sampaio & Dalu Yang & Souptik Barua & Huamin Wang & Arvind Rao & James P. Allison & Valerie S. LeBleu & Raghu Kalluri - 1-13 Bone-in-culture array as a platform to model early-stage bone metastases and discover anti-metastasis therapies
by Hai Wang & Lin Tian & Amit Goldstein & Jun Liu & Hin-Ching Lo & Kuanwei Sheng & Thomas Welte & Stephen T.C. Wong & Zbigniew Gugala & Fabio Stossi & Chenghang Zong & Zonghai Li & Michael A. Mancini & Xiang H.-F. Zhang - 1-13 Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20
by Gan Liu & Luting Zhou & Hai Zhang & Rong Chen & Ye Zhang & Ling Li & Jun-Yu Lu & Hui Jiang & Dong Liu & Shasha Qi & Ying-Ming Jiang & Kai Yin & Zhifang Xie & Yuguang Shi & Yong Liu & Xuetao Cao & Yu-Xia Chen & Dajin Zou & Weiping J. Zhang - 1-13 Cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites
by Esther Rajendran & Sanduni V. Hapuarachchi & Catherine M. Miller & Stephen J. Fairweather & Yeping Cai & Nicholas C. Smith & Ian A. Cockburn & Stefan Bröer & Kiaran Kirk & Giel G. van Dooren - 1-13 DNA single-strand break-induced DNA damage response causes heart failure
by Tomoaki Higo & Atsuhiko T. Naito & Tomokazu Sumida & Masato Shibamoto & Katsuki Okada & Seitaro Nomura & Akito Nakagawa & Toshihiro Yamaguchi & Taku Sakai & Akihito Hashimoto & Yuki Kuramoto & Masamichi Ito & Shungo Hikoso & Hiroshi Akazawa & Jong-Kook Lee & Ichiro Shiojima & Peter J. McKinnon & Yasushi Sakata & Issei Komuro - 1-13 Pten is necessary for the quiescence and maintenance of adult muscle stem cells
by Feng Yue & Pengpeng Bi & Chao Wang & Tizhong Shan & Yaohui Nie & Timothy L. Ratliff & Timothy P. Gavin & Shihuan Kuang - 1-13 Dissection of goadsporin biosynthesis by in vitro reconstitution leading to designer analogues expressed in vivo
by Taro Ozaki & Kona Yamashita & Yuki Goto & Morito Shimomura & Shohei Hayashi & Shumpei Asamizu & Yoshinori Sugai & Haruo Ikeda & Hiroaki Suga & Hiroyasu Onaka - 1-13 Induced p53 loss in mouse luminal cells causes clonal expansion and development of mammary tumours
by Luwei Tao & Dongxi Xiang & Ying Xie & Roderick T. Bronson & Zhe Li - 1-13 Global site-specific N-glycosylation analysis of HIV envelope glycoprotein
by Liwei Cao & Jolene K. Diedrich & Daniel W. Kulp & Matthias Pauthner & Lin He & Sung-Kyu Robin Park & Devin Sok & Ching Yao Su & Claire M. Delahunty & Sergey Menis & Raiees Andrabi & Javier Guenaga & Erik Georgeson & Michael Kubitz & Yumiko Adachi & Dennis R. Burton & William R. Schief & John R. Yates III & James C. Paulson - 1-13 The ancient CYP716 family is a major contributor to the diversification of eudicot triterpenoid biosynthesis
by Karel Miettinen & Jacob Pollier & Dieter Buyst & Philipp Arendt & René Csuk & Sven Sommerwerk & Tessa Moses & Jan Mertens & Prashant D Sonawane & Laurens Pauwels & Asaph Aharoni & José Martins & David R. Nelson & Alain Goossens - 1-13 MECP2 regulates cortical plasticity underlying a learned behaviour in adult female mice
by Keerthi Krishnan & Billy Y. B. Lau & Gabrielle Ewall & Z. Josh Huang & Stephen D. Shea - 1-13 Mutualism supports biodiversity when the direct competition is weak
by Alberto Pascual-García & Ugo Bastolla - 1-13 VGLL4 targets a TCF4–TEAD4 complex to coregulate Wnt and Hippo signalling in colorectal cancer
by Shi Jiao & Chuanchuan Li & Qian Hao & Haofei Miao & Lei Zhang & Lin Li & Zhaocai Zhou - 1-13 Transient auditory nerve demyelination as a new mechanism for hidden hearing loss
by Guoqiang Wan & Gabriel Corfas - 1-13 Pervasive translational regulation of the cell signalling circuitry underlies mammalian development
by Kotaro Fujii & Zhen Shi & Olena Zhulyn & Nicolas Denans & Maria Barna - 1-13 Erythrocytes retain hypoxic adenosine response for faster acclimatization upon re-ascent
by Anren Song & Yujin Zhang & Leng Han & Gennady G. Yegutkin & Hong Liu & Kaiqi Sun & Angelo D’Alessandro & Jessica Li & Harry Karmouty-Quintana & Takayuki Iriyama & Tingting Weng & Shushan Zhao & Wei Wang & Hongyu Wu & Travis Nemkov & Andrew W. Subudhi & Sonja Jameson-Van Houten & Colleen G. Julian & Andrew T. Lovering & Kirk C. Hansen & Hong Zhang & Mikhail Bogdanov & William Dowhan & Jianping Jin & Rodney E. Kellems & Holger K. Eltzschig & Michael Blackburn & Robert C. Roach & Yang Xia - 1-13 PAXX promotes KU accumulation at DNA breaks and is essential for end-joining in XLF-deficient mice
by Xiangyu Liu & Zhengping Shao & Wenxia Jiang & Brian J. Lee & Shan Zha - 1-13 Host-inherent variability influences the transcriptional response of Staphylococcus aureus during in vivo infection
by Robert Thänert & Oliver Goldmann & Andreas Beineke & Eva Medina - 1-13 Mass spectrometric monitoring of interfacial photoelectron transfer and imaging of active crystalline facets of semiconductors
by Hongying Zhong & Juan Zhang & Xuemei Tang & Wenyang Zhang & Ruowei Jiang & Rui Li & Disong Chen & Peng Wang & Zhiwei Yuan - 1-13 Phylogenetic analysis of metastatic progression in breast cancer using somatic mutations and copy number aberrations
by David Brown & Dominiek Smeets & Borbála Székely & Denis Larsimont & A. Marcell Szász & Pierre-Yves Adnet & Françoise Rothé & Ghizlane Rouas & Zsófia I. Nagy & Zsófia Faragó & Anna-Mária Tőkés & Magdolna Dank & Gyöngyvér Szentmártoni & Nóra Udvarhelyi & Gabriele Zoppoli & Lajos Pusztai & Martine Piccart & Janina Kulka & Diether Lambrechts & Christos Sotiriou & Christine Desmedt - 1-13 Lamin B1 is required for mature neuron-specific gene expression during olfactory sensory neuron differentiation
by Crystal M. Gigante & Michele Dibattista & Frederick N. Dong & Xiaobin Zheng & Sibiao Yue & Stephen G. Young & Johannes Reisert & Yixian Zheng & Haiqing Zhao - 1-13 Macrocycle peptides delineate locked-open inhibition mechanism for microorganism phosphoglycerate mutases
by Hao Yu & Patricia Dranchak & Zhiru Li & Ryan MacArthur & Matthew S. Munson & Nurjahan Mehzabeen & Nathan J. Baird & Kevin P. Battalie & David Ross & Scott Lovell & Clotilde K. S. Carlow & Hiroaki Suga & James Inglese - 1-13 Accelerating the search for the missing proteins in the human proteome
by Mark S. Baker & Seong Beom Ahn & Abidali Mohamedali & Mohammad T. Islam & David Cantor & Peter D. Verhaert & Susan Fanayan & Samridhi Sharma & Edouard C. Nice & Mark Connor & Shoba Ranganathan - 1-13 A Lin28 homologue reprograms differentiated cells to stem cells in the moss Physcomitrella patens
by Chen Li & Yusuke Sako & Akihiro Imai & Tomoaki Nishiyama & Kari Thompson & Minoru Kubo & Yuji Hiwatashi & Yukiko Kabeya & Dale Karlson & Shu-Hsing Wu & Masaki Ishikawa & Takashi Murata & Philip N. Benfey & Yoshikatsu Sato & Yosuke Tamada & Mitsuyasu Hasebe - 1-14 Dissecting cell-type-specific roles of androgen receptor in prostate homeostasis and regeneration through lineage tracing
by Qing Xie & Yueli Liu & Tao Cai & Corrigan Horton & Joshua Stefanson & Zhu A. Wang - 1-14 Macrophages induce AKT/β-catenin-dependent Lgr5+ stem cell activation and hair follicle regeneration through TNF
by Xusheng Wang & Haiyan Chen & Ruiyun Tian & Yiling Zhang & Marina S. Drutskaya & Chengmei Wang & Jianfeng Ge & Zhimeng Fan & Deqiang Kong & Xiaoxiao Wang & Ting Cai & Ying Zhou & Jingwen Wang & Jinmei Wang & Shan Wang & Zhihai Qin & Huanhuan Jia & Yue Wu & Jia Liu & Sergei A. Nedospasov & Edward E. Tredget & Mei Lin & Jianjun Liu & Yuyang Jiang & Yaojiong Wu - 1-14 A signature motif in LIM proteins mediates binding to checkpoint proteins and increases tumour radiosensitivity
by Xiaojie Xu & Zhongyi Fan & Chaoyang Liang & Ling Li & Lili Wang & Yingchun Liang & Jun Wu & Shaohong Chang & Zhifeng Yan & Zhaohui Lv & Jing Fu & Yang Liu & Shuai Jin & Tao Wang & Tian Hong & Yishan Dong & Lihua Ding & Long Cheng & Rui Liu & Shenbo Fu & Shunchang Jiao & Qinong Ye - 1-14 Cytoglobin regulates blood pressure and vascular tone through nitric oxide metabolism in the vascular wall
by Xiaoping Liu & Mohamed A. El-Mahdy & James Boslett & Saradhadevi Varadharaj & Craig Hemann & Tamer M. Abdelghany & Raed S. Ismail & Sean C. Little & Danlei Zhou & Le Thi Thanh Thuy & Norifumi Kawada & Jay L. Zweier - 1-14 Structural basis of ligand interaction with atypical chemokine receptor 3
by Martin Gustavsson & Liwen Wang & Noortje van Gils & Bryan S. Stephens & Penglie Zhang & Thomas J. Schall & Sichun Yang & Ruben Abagyan & Mark R. Chance & Irina Kufareva & Tracy M. Handel - 1-14 Usp9x regulates Ets-1 ubiquitination and stability to control NRAS expression and tumorigenicity in melanoma
by Harish Potu & Luke F. Peterson & Malathi Kandarpa & Anupama Pal & Hanshi Sun & Alison Durham & Paul W. Harms & Peter C. Hollenhorst & Ugur Eskiocak & Moshe Talpaz & Nicholas J. Donato - 1-14 Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68
by Ning Huang & Yuqing Xia & Donghui Zhang & Song Wang & Yitian Bao & Runsheng He & Junlin Teng & Jianguo Chen - 1-14 DNA replication licensing factor Cdc6 and Plk4 kinase antagonistically regulate centrosome duplication via Sas-6
by Xiaowei Xu & Shijiao Huang & Boyan Zhang & Fan Huang & Wangfei Chi & Jingyan Fu & Gang Wang & Si Li & Qing Jiang & Chuanmao Zhang - 1-14 FRET biosensor uncovers cAMP nano-domains at β-adrenergic targets that dictate precise tuning of cardiac contractility
by Nicoletta C. Surdo & Marco Berrera & Andreas Koschinski & Marcella Brescia & Matias R. Machado & Carolyn Carr & Peter Wright & Julia Gorelik & Stefano Morotti & Eleonora Grandi & Donald M. Bers & Sergio Pantano & Manuela Zaccolo - 1-14 SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophages
by Lin Luo & Nilesh J. Bokil & Adam A. Wall & Ronan Kapetanovic & Natalie M. Lansdaal & Faustine Marceline & Belinda J. Burgess & Samuel J. Tong & Zhong Guo & Kirill Alexandrov & Ian L. Ross & Margaret L. Hibbs & Jennifer L. Stow & Matthew J. Sweet - 1-14 Nur77 suppresses hepatocellular carcinoma via switching glucose metabolism toward gluconeogenesis through attenuating phosphoenolpyruvate carboxykinase sumoylation
by Xue-li Bian & Hang-zi Chen & Peng-bo Yang & Ying-ping Li & Fen-na Zhang & Jia-yuan Zhang & Wei-jia Wang & Wen-xiu Zhao & Sheng Zhang & Qi-tao Chen & Yu Zheng & Xiao-yu Sun & Xiao-min Wang & Kun-Yi Chien & Qiao Wu - 1-14 Structure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation
by Matthew Y. Tang & Marta Vranas & Andrea I. Krahn & Shayal Pundlik & Jean- François Trempe & Edward A. Fon - 1-14 Connecting genetic risk to disease end points through the human blood plasma proteome
by Karsten Suhre & Matthias Arnold & Aditya Mukund Bhagwat & Richard J. Cotton & Rudolf Engelke & Johannes Raffler & Hina Sarwath & Gaurav Thareja & Annika Wahl & Robert Kirk DeLisle & Larry Gold & Marija Pezer & Gordan Lauc & Mohammed A. El-Din Selim & Dennis O. Mook-Kanamori & Eman K. Al-Dous & Yasmin A. Mohamoud & Joel Malek & Konstantin Strauch & Harald Grallert & Annette Peters & Gabi Kastenmüller & Christian Gieger & Johannes Graumann - 1-14 Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity
by Marjolein Soethoudt & Uwe Grether & Jürgen Fingerle & Travis W. Grim & Filomena Fezza & Luciano de Petrocellis & Christoph Ullmer & Benno Rothenhäusler & Camille Perret & Noortje van Gils & David Finlay & Christa MacDonald & Andrea Chicca & Marianela Dalghi Gens & Jordyn Stuart & Henk de Vries & Nicolina Mastrangelo & Lizi Xia & Georgios Alachouzos & Marc P. Baggelaar & Andrea Martella & Elliot D. Mock & Hui Deng & Laura H. Heitman & Mark Connor & Vincenzo Di Marzo & Jürg Gertsch & Aron H. Lichtman & Mauro Maccarrone & Pal Pacher & Michelle Glass & Mario van der Stelt - 1-14 Temporal and compartment-specific signals coordinate mitotic exit with spindle position
by Ayse Koca Caydasi & Anton Khmelinskii & Rafael Duenas-Sanchez & Bahtiyar Kurtulmus & Michael Knop & Gislene Pereira - 1-14 Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer’s disease
by Annalisa Nobili & Emanuele Claudio Latagliata & Maria Teresa Viscomi & Virve Cavallucci & Debora Cutuli & Giacomo Giacovazzo & Paraskevi Krashia & Francesca Romana Rizzo & Ramona Marino & Mauro Federici & Paola De Bartolo & Daniela Aversa & Maria Concetta Dell’Acqua & Alberto Cordella & Marco Sancandi & Flavio Keller & Laura Petrosini & Stefano Puglisi-Allegra & Nicola Biagio Mercuri & Roberto Coccurello & Nicola Berretta & Marcello D’Amelio - 1-14 Prenatal thalamic waves regulate cortical area size prior to sensory processing
by Verónica Moreno-Juan & Anton Filipchuk & Noelia Antón-Bolaños & Cecilia Mezzera & Henrik Gezelius & Belen Andrés & Luis Rodríguez-Malmierca & Rafael Susín & Olivier Schaad & Takuji Iwasato & Roland Schüle & Michael Rutlin & Sacha Nelson & Sebastien Ducret & Miguel Valdeolmillos & Filippo M. Rijli & Guillermina López-Bendito - 1-14 Astrocyte deletion of Bmal1 alters daily locomotor activity and cognitive functions via GABA signalling
by Olga Barca-Mayo & Meritxell Pons-Espinal & Philipp Follert & Andrea Armirotti & Luca Berdondini & Davide De Pietri Tonelli - 1-14 Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma
by Huai-Qiang Ju & Haoqiang Ying & Tian Tian & Jianhua Ling & Jie Fu & Yu Lu & Min Wu & Lifeng Yang & Abhinav Achreja & Gang Chen & Zhuonan Zhuang & Huamin Wang & Deepak Nagrath & Jun Yao & Mien-Chie Hung & Ronald A. DePinho & Peng Huang & Rui-Hua Xu & Paul J. Chiao - 1-14 Intrauterine Zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes
by Meghan S. Vermillion & Jun Lei & Yahya Shabi & Victoria K. Baxter & Nathan P. Crilly & Michael McLane & Diane E. Griffin & Andrew Pekosz & Sabra L. Klein & Irina Burd - 1-14 A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer
by Paola A. Betancur & Brian J. Abraham & Ying Y. Yiu & Stephen B. Willingham & Farnaz Khameneh & Mark Zarnegar & Angera H. Kuo & Kelly McKenna & Yoko Kojima & Nicholas J. Leeper & Po Ho & Phung Gip & Tomek Swigut & Richard I. Sherwood & Michael F. Clarke & George Somlo & Richard A. Young & Irving L. Weissman - 1-14 Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death
by Corey Rogers & Teresa Fernandes-Alnemri & Lindsey Mayes & Diana Alnemri & Gino Cingolani & Emad S. Alnemri - 1-14 Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity
by Dmitriy Zamarin & Rikke B. Holmgaard & Jacob Ricca & Tamar Plitt & Peter Palese & Padmanee Sharma & Taha Merghoub & Jedd D. Wolchok & James P. Allison - 1-14 DNA damage response inhibition at dysfunctional telomeres by modulation of telomeric DNA damage response RNAs
by Francesca Rossiello & Julio Aguado & Sara Sepe & Fabio Iannelli & Quan Nguyen & Sethuramasundaram Pitchiaya & Piero Carninci & Fabrizio d’Adda di Fagagna - 1-14 PTENβ is an alternatively translated isoform of PTEN that regulates rDNA transcription
by Hui Liang & Xi Chen & Qi Yin & Danhui Ruan & Xuyang Zhao & Cong Zhang & Michael A. McNutt & Yuxin Yin - 1-14 T cell costimulation blockade blunts pressure overload-induced heart failure
by Marinos Kallikourdis & Elisa Martini & Pierluigi Carullo & Claudia Sardi & Giuliana Roselli & Carolina M. Greco & Debora Vignali & Federica Riva & Anne Marie Ormbostad Berre & Tomas O. Stølen & Andrea Fumero & Giuseppe Faggian & Elisa Di Pasquale & Leonardo Elia & Cristiano Rumio & Daniele Catalucci & Roberto Papait & Gianluigi Condorelli - 1-14 Chemical labelling for visualizing native AMPA receptors in live neurons
by Sho Wakayama & Shigeki Kiyonaka & Itaru Arai & Wataru Kakegawa & Shinji Matsuda & Keiji Ibata & Yuri L. Nemoto & Akihiro Kusumi & Michisuke Yuzaki & Itaru Hamachi - 1-14 IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population
by Daniele C. Nascimento & Paulo H. Melo & Annie R. Piñeros & Raphael G. Ferreira & David F. Colón & Paula B. Donate & Fernanda V. Castanheira & Aline Gozzi & Paula G. Czaikoski & Wanda Niedbala & Marcos C. Borges & Dario S. Zamboni & Foo Y. Liew & Fernando Q. Cunha & Jose C. Alves-Filho - 1-14 Local inhibition of microtubule dynamics by dynein is required for neuronal cargo distribution
by Shaul Yogev & Celine I. Maeder & Roshni Cooper & Mark Horowitz & Adam G. Hendricks & Kang Shen - 1-14 Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression
by Halime Kalkavan & Piyush Sharma & Stefan Kasper & Iris Helfrich & Aleksandra A. Pandyra & Asmae Gassa & Isabel Virchow & Lukas Flatz & Tim Brandenburg & Sukumar Namineni & Mathias Heikenwalder & Bastian Höchst & Percy A. Knolle & Guido Wollmann & Dorothee von Laer & Ingo Drexler & Jessica Rathbun & Paula M. Cannon & Stefanie Scheu & Jens Bauer & Jagat Chauhan & Dieter Häussinger & Gerald Willimsky & Max Löhning & Dirk Schadendorf & Sven Brandau & Martin Schuler & Philipp A. Lang & Karl S. Lang - 1-14 Integrated genomic analyses of de novo pathways underlying atypical meningiomas
by Akdes Serin Harmancı & Mark W. Youngblood & Victoria E. Clark & Süleyman Coşkun & Octavian Henegariu & Daniel Duran & E. Zeynep Erson-Omay & Leon D. Kaulen & Tong Ihn Lee & Brian J. Abraham & Matthias Simon & Boris Krischek & Marco Timmer & Roland Goldbrunner & S. Bülent Omay & Jacob Baranoski & Burçin Baran & Geneive Carrión-Grant & Hanwen Bai & Ketu Mishra-Gorur & Johannes Schramm & Jennifer Moliterno & Alexander O. Vortmeyer & Kaya Bilgüvar & Katsuhito Yasuno & Richard A. Young & Murat Günel - 1-14 Glucocorticoid receptor signalling activates YAP in breast cancer
by Giovanni Sorrentino & Naomi Ruggeri & Alessandro Zannini & Eleonora Ingallina & Rebecca Bertolio & Carolina Marotta & Carmelo Neri & Elisa Cappuzzello & Mattia Forcato & Antonio Rosato & Miguel Mano & Silvio Bicciato & Giannino Del Sal - 1-14 Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme
by Weijun Feng & Daisuke Kawauchi & Huiqin Körkel-Qu & Huan Deng & Elisabeth Serger & Laura Sieber & Jenna Ariel Lieberman & Silvia Jimeno-González & Sander Lambo & Bola S. Hanna & Yassin Harim & Malin Jansen & Anna Neuerburg & Olga Friesen & Marc Zuckermann & Vijayanad Rajendran & Jan Gronych & Olivier Ayrault & Andrey Korshunov & David T. W. Jones & Marcel Kool & Paul A. Northcott & Peter Lichter & Felipe Cortés-Ledesma & Stefan M. Pfister & Hai-Kun Liu - 1-14 RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome
by Yingying Zhang & Sheng Sean Su & Shubo Zhao & Zhentao Yang & Chuan-Qi Zhong & Xin Chen & Qixu Cai & Zhang-Hua Yang & Deli Huang & Rui Wu & Jiahuai Han - 1-14 Loss of the Arp2/3 complex component ARPC1B causes platelet abnormalities and predisposes to inflammatory disease
by Walter H. A. Kahr & Fred G. Pluthero & Abdul Elkadri & Neil Warner & Marko Drobac & Chang Hua Chen & Richard W. Lo & Ling Li & Ren Li & Qi Li & Cornelia Thoeni & Jie Pan & Gabriella Leung & Irene Lara-Corrales & Ryan Murchie & Ernest Cutz & Ronald M. Laxer & Julia Upton & Chaim M. Roifman & Rae S. M. Yeung & John H Brumell & Aleixo M Muise - 1-14 Functional roles of Aves class-specific cis-regulatory elements on macroevolution of bird-specific features
by Ryohei Seki & Cai Li & Qi Fang & Shinichi Hayashi & Shiro Egawa & Jiang Hu & Luohao Xu & Hailin Pan & Mao Kondo & Tomohiko Sato & Haruka Matsubara & Namiko Kamiyama & Keiichi Kitajima & Daisuke Saito & Yang Liu & M. Thomas P. Gilbert & Qi Zhou & Xing Xu & Toshihiko Shiroishi & Naoki Irie & Koji Tamura & Guojie Zhang - 1-14 Constitutive smooth muscle tumour necrosis factor regulates microvascular myogenic responsiveness and systemic blood pressure
by Jeffrey T. Kroetsch & Andrew S. Levy & Hangjun Zhang & Roozbeh Aschar-Sobbi & Darcy Lidington & Stefan Offermanns & Sergei A. Nedospasov & Peter H. Backx & Scott P. Heximer & Steffen-Sebastian Bolz - 1-14 Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface
by HaoRan Tang & Leo Leung & Grazia Saturno & Amaya Viros & Duncan Smith & Gianpiero Di Leva & Eamonn Morrison & Dan Niculescu-Duvaz & Filipa Lopes & Louise Johnson & Nathalie Dhomen & Caroline Springer & Richard Marais - 1-14 The OncoPPi network of cancer-focused protein–protein interactions to inform biological insights and therapeutic strategies
by Zenggang Li & Andrei A. Ivanov & Rina Su & Valentina Gonzalez-Pecchi & Qi Qi & Songlin Liu & Philip Webber & Elizabeth McMillan & Lauren Rusnak & Cau Pham & Xiaoqian Chen & Xiulei Mo & Brian Revennaugh & Wei Zhou & Adam Marcus & Sahar Harati & Xiang Chen & Margaret A. Johns & Michael A. White & Carlos S. Moreno & Lee A. D. Cooper & Yuhong Du & Fadlo R. Khuri & Haian Fu - 1-14 MicroRNA-141 suppresses prostate cancer stem cells and metastasis by targeting a cohort of pro-metastasis genes
by Can Liu & Ruifang Liu & Dingxiao Zhang & Qu Deng & Bigang Liu & Hsueh-Ping Chao & Kiera Rycaj & Yoko Takata & Kevin Lin & Yue Lu & Yi Zhong & John Krolewski & Jianjun Shen & Dean G. Tang - 1-14 Parvalbumin-expressing interneurons coordinate hippocampal network dynamics required for memory consolidation
by Nicolette Ognjanovski & Samantha Schaeffer & Jiaxing Wu & Sima Mofakham & Daniel Maruyama & Michal Zochowski & Sara J. Aton - 1-14 An allosteric conduit facilitates dynamic multisite substrate recognition by the SCFCdc4 ubiquitin ligase
by Veronika Csizmok & Stephen Orlicky & Jing Cheng & Jianhui Song & Alaji Bah & Neda Delgoshaie & Hong Lin & Tanja Mittag & Frank Sicheri & Hue Sun Chan & Mike Tyers & Julie D. Forman-Kay - 1-14 IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2
by Christoph Jandl & Sue M. Liu & Pablo F. Cañete & Joanna Warren & William E. Hughes & Alexis Vogelzang & Kylie Webster & Maria E. Craig & Gulbu Uzel & Alexander Dent & Polina Stepensky & Bärbel Keller & Klaus Warnatz & Jonathan Sprent & Cecile King - 1-14 Disrupted neuronal maturation in Angelman syndrome-derived induced pluripotent stem cells
by James J. Fink & Tiwanna M. Robinson & Noelle D. Germain & Carissa L. Sirois & Kaitlyn A. Bolduc & Amanda J. Ward & Frank Rigo & Stormy J. Chamberlain & Eric S. Levine - 1-14 Updating temporal expectancy of an aversive event engages striatal plasticity under amygdala control
by Glenn Dallérac & Michael Graupner & Jeroen Knippenberg & Raquel Chacon Ruiz Martinez & Tatiane Ferreira Tavares & Lucille Tallot & Nicole El Massioui & Anna Verschueren & Sophie Höhn & Julie Boulanger Bertolus & Alex Reyes & Joseph E. LeDoux & Glenn E. Schafe & Lorenzo Diaz-Mataix & Valérie Doyère - 1-14 BMP restricts stemness of intestinal Lgr5+ stem cells by directly suppressing their signature genes
by Zhen Qi & Yehua Li & Bing Zhao & Chi Xu & Yuan Liu & Haonan Li & Bingjie Zhang & Xinquan Wang & Xiao Yang & Wei Xie & Baojie Li & Jing-Dong Jackie Han & Ye-Guang Chen - 1-14 Glia-derived ATP inversely regulates excitability of pyramidal and CCK-positive neurons
by Zhibing Tan & Yu Liu & Wang Xi & Hui-fang Lou & Liya Zhu & Zhifei Guo & Lin Mei & Shumin Duan - 1-14 Elevated levels of Bcl-3 inhibits Treg development and function resulting in spontaneous colitis
by Sonja Reißig & Yilang Tang & Alexei Nikolaev & Katharina Gerlach & Christine Wolf & Kathrin Davari & Christian Gallus & Joumana Masri & Ilgiz A. Mufazalov & Markus F. Neurath & F. Thomas Wunderlich & Jörn M. Schattenberg & Peter R. Galle & Benno Weigmann & Ari Waisman & Elke Glasmacher & Nadine Hövelmeyer - 1-14 Specialized interfaces of Smc5/6 control hinge stability and DNA association
by Aaron Alt & Hung Q. Dang & Owen S. Wells & Luis M. Polo & Matt A. Smith & Grant A. McGregor & Thomas Welte & Alan R. Lehmann & Laurence H. Pearl & Johanne M. Murray & Antony W. Oliver - 1-14 Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression
by Weikang Cai & Masaji Sakaguchi & Andre Kleinridders & Gonzalo Gonzalez-Del Pino & Jonathan M. Dreyfuss & Brian T. O’Neill & Alfred K. Ramirez & Hui Pan & Jonathon N. Winnay & Jeremie Boucher & Michael J. Eck & C. Ronald Kahn - 1-14 JAK/STAT controls organ size and fate specification by regulating morphogen production and signalling
by Carles Recasens-Alvarez & Ana Ferreira & Marco Milán - 1-14 The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression
by Ryuhjin Ahn & Valérie Sabourin & Alicia M. Bolt & Steven Hébert & Stephanie Totten & Nicolas De Jay & Maria Carolina Festa & Yoon Kow Young & Young Kyuen Im & Tony Pawson & Antonis E. Koromilas & William J. Muller & Koren K. Mann & Claudia L. Kleinman & Josie Ursini-Siegel - 1-14 Activation of E-prostanoid 3 receptor in macrophages facilitates cardiac healing after myocardial infarction
by Juan Tang & Yujun Shen & Guilin Chen & Qiangyou Wan & Kai Wang & Jian Zhang & Jing Qin & Guizhu Liu & Shengkai Zuo & Bo Tao & Yu Yu & Junwen Wang & Michael Lazarus & Ying Yu - 1-14 Defining stem cell dynamics and migration during wound healing in mouse skin epidermis
by Mariaceleste Aragona & Sophie Dekoninck & Steffen Rulands & Sandrine Lenglez & Guilhem Mascré & Benjamin D. Simons & Cédric Blanpain - 1-14 TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling
by Liam A. Hurst & Benjamin J. Dunmore & Lu Long & Alexi Crosby & Rafia Al-Lamki & John Deighton & Mark Southwood & Xudong Yang & Marko Z. Nikolic & Blanca Herrera & Gareth J. Inman & John R. Bradley & Amer A. Rana & Paul D. Upton & Nicholas W. Morrell - 1-14 Selective molecular impairment of spontaneous neurotransmission modulates synaptic efficacy
by Devon C. Crawford & Denise M. O. Ramirez & Brent Trauterman & Lisa M. Monteggia & Ege T. Kavalali - 1-14 A tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism
by Lavinia Palamiuc & Tallie Noble & Emily Witham & Harkaranveer Ratanpal & Megan Vaughan & Supriya Srinivasan - 1-14 Determining the bacterial cell biology of Planctomycetes
by Christian Boedeker & Margarete Schüler & Greta Reintjes & Olga Jeske & Muriel C. F. van Teeseling & Mareike Jogler & Patrick Rast & Daniela Borchert & Damien P. Devos & Martin Kucklick & Miroslava Schaffer & Roberto Kolter & Laura van Niftrik & Susanne Engelmann & Rudolf Amann & Manfred Rohde & Harald Engelhardt & Christian Jogler - 1-14 Layer-specificity in the effects of attention and working memory on activity in primary visual cortex
by Timo van Kerkoerle & Matthew W. Self & Pieter R. Roelfsema - 1-14 Epigenetically-driven anatomical diversity of synovial fibroblasts guides joint-specific fibroblast functions
by Mojca Frank-Bertoncelj & Michelle Trenkmann & Kerstin Klein & Emmanuel Karouzakis & Hubert Rehrauer & Anna Bratus & Christoph Kolling & Maria Armaka & Andrew Filer & Beat A. Michel & Renate E. Gay & Christopher D. Buckley & George Kollias & Steffen Gay & Caroline Ospelt - 1-14 Role for formin-like 1-dependent acto-myosin assembly in lipid droplet dynamics and lipid storage
by Simon G. Pfisterer & Gergana Gateva & Peter Horvath & Juho Pirhonen & Veijo T. Salo & Leena Karhinen & Markku Varjosalo & Samppa J. Ryhänen & Pekka Lappalainen & Elina Ikonen - 1-14 Epithelial tension in the second heart field promotes mouse heart tube elongation
by Alexandre Francou & Christopher De Bono & Robert G. Kelly - 1-14 Structure of the homodimeric androgen receptor ligand-binding domain
by Marta Nadal & Stefan Prekovic & Nerea Gallastegui & Christine Helsen & Montserrat Abella & Karolina Zielinska & Marina Gay & Marta Vilaseca & Marta Taulès & Adriaan B. Houtsmuller & Martin E. van Royen & Frank Claessens & Pablo Fuentes-Prior & Eva Estébanez-Perpiñá - 1-14 SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts
by Zhan Xu & Matthew B. Greenblatt & Guang Yan & Heng Feng & Jun Sun & Sutada Lotinun & Nicholas Brady & Roland Baron & Laurie H. Glimcher & Weiguo Zou - 1-14 Pancancer modelling predicts the context-specific impact of somatic mutations on transcriptional programs
by Hatice U. Osmanbeyoglu & Eneda Toska & Carmen Chan & José Baselga & Christina S. Leslie - 1-14 K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression
by Zhenyue Hao & Yi Sheng & Gordon S. Duncan & Wanda Y. Li & Carmen Dominguez & Jennifer Sylvester & Yu-Wen Su & Gloria H.Y. Lin & Bryan E. Snow & Dirk Brenner & Annick You-Ten & Jillian Haight & Satoshi Inoue & Andrew Wakeham & Alisha Elford & Sara Hamilton & Yi Liang & Juan C. Zúñiga-Pflücker & Housheng Hansen He & Pamela S. Ohashi & Tak W. Mak - 1-14 Self-organizing actin patterns shape membrane architecture but not cell mechanics
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