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Parallel comparison of risk factors between progression of organic stenosis in the coronary arteries and onset of acute coronary syndrome by covariance structure analysis

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  • Kazuo Ogawa
  • Kosuke Minai
  • Makoto Kawai
  • Toshikazu Tanaka
  • Tomohisa Nagoshi
  • Takayuki Ogawa
  • Michihiro Yoshimura

Abstract

Background: It is widely accepted that progression of organic stenosis in the coronary arteries and onset of acute coronary syndrome (ACS) are similar in the development of atherosclerosis. However, the extent of the association of each risk factor with the respective pathological conditions has not been fully elucidated. Objectives: We investigated the differences in risk factors between these conditions using a statistical procedure. Methods: The study population consisted of 1,029 patients with ischemic heart disease (IHD). We divided the study population into two groups (ACS and non-ACS) and by diseased vessels (organic stenosis). Covariance structure analysis was simultaneously performed in one equation model for determination and comparison of the risk factors for organic stenosis and ACS. Results: The analysis revealed that age (standardized regression coefficient, β: 0.206, P

Suggested Citation

  • Kazuo Ogawa & Kosuke Minai & Makoto Kawai & Toshikazu Tanaka & Tomohisa Nagoshi & Takayuki Ogawa & Michihiro Yoshimura, 2017. "Parallel comparison of risk factors between progression of organic stenosis in the coronary arteries and onset of acute coronary syndrome by covariance structure analysis," PLOS ONE, Public Library of Science, vol. 12(3), pages 1-16, March.
    • Handle: RePEc:plo:pone00:0173898
    DOI: 10.1371/journal.pone.0173898
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