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Specimen origin, type and testing laboratory are linked to longer turnaround times for HIV viral load testing in Malawi

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  • Peter A Minchella
  • Geoffrey Chipungu
  • Andrea A Kim
  • Abdoulaye Sarr
  • Hammad Ali
  • Reuben Mwenda
  • John N Nkengasong
  • Daniel Singer

Abstract

Background: Efforts to reach UNAIDS’ treatment and viral suppression targets have increased demand for viral load (VL) testing and strained existing laboratory networks, affecting turnaround time. Longer VL turnaround times delay both initiation of formal adherence counseling and switches to second-line therapy for persons failing treatment and contribute to poorer health outcomes. Methods: We utilized descriptive statistics and logistic regression to analyze VL testing data collected in Malawi between January 2013 and March 2016. The primary outcomes assessed were greater-than-median pretest phase turnaround time (days elapsed from specimen collection to receipt at the laboratory) and greater-than-median test phase turnaround time (days from receipt to testing). Results: The median number of days between specimen collection and testing increased 3-fold between 2013 (8 days, interquartile range (IQR) = 6–16) and 2015 (24, IQR = 13–39) (p

Suggested Citation

  • Peter A Minchella & Geoffrey Chipungu & Andrea A Kim & Abdoulaye Sarr & Hammad Ali & Reuben Mwenda & John N Nkengasong & Daniel Singer, 2017. "Specimen origin, type and testing laboratory are linked to longer turnaround times for HIV viral load testing in Malawi," PLOS ONE, Public Library of Science, vol. 12(2), pages 1-13, February.
    • Handle: RePEc:plo:pone00:0173009
    DOI: 10.1371/journal.pone.0173009
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