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Relationship between pre-anesthetic and intra-anesthetic airway resistance in patients undergoing general anesthesia: A prospective observational study

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  • Takamitsu Ikeda
  • Kanji Uchida
  • Yasuhiro Yamauchi
  • Takahide Nagase
  • Koji Oba
  • Yoshitsugu Yamada

Abstract

Surgery patients in Japan undergo routine spirometry testing prior to general anesthesia. The use of a flow sensor during general anesthesia has recently become common. However, it is not certain whether the information derived from flow-volume curves is being adequately used for mechanical ventilation management during general anesthesia. So far, there have been no attempts to calculate airway resistance using flow-volume curves. Therefore, we performed a prospective, observational study to investigate the relationship between pre-anesthetic and intra-anesthetic airway resistance in patients scheduled for surgery under general anesthesia. We calculated pre-anesthetic and intra-anesthetic airway resistance in each patient, based on the slopes of flow-volume curves obtained prior to and during general anesthesia. We also calculated endotracheal tube resistance to correct the intra-anesthetic airway resistance values calculated. A total of 526 patients were included in the study, and 98 patients had a forced expiratory volume in the first second/forced vital capacity ratio of

Suggested Citation

  • Takamitsu Ikeda & Kanji Uchida & Yasuhiro Yamauchi & Takahide Nagase & Koji Oba & Yoshitsugu Yamada, 2017. "Relationship between pre-anesthetic and intra-anesthetic airway resistance in patients undergoing general anesthesia: A prospective observational study," PLOS ONE, Public Library of Science, vol. 12(2), pages 1-16, February.
    • Handle: RePEc:plo:pone00:0172421
    DOI: 10.1371/journal.pone.0172421
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