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Effects of the Share 35 Rule on Waitlist and Liver Transplantation Outcomes for Patients with Hepatocellular Carcinoma

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  • Kristopher P Croome
  • David D Lee
  • Denise Harnois
  • C Burcin Taner

Abstract

Introduction: Several studies have investigated the effects following the implementation of the “Share 35” policy; however none have investigated what effect this policy change has had on waitlist and liver transplantation (LT) outcomes for hepatocellular carcinoma(HCC). Methods: Data were obtained from the UNOS database and a comparison of the 2 years post-Share 35 with data from the 2 years pre-Share 35 was performed. Results: In the pre-Share35 era, 23% of LT were performed for HCC exceptions compared to 22% of LT in the post-Share35 era (p = 0.21). No difference in wait-time for HCC patients was seen in any of the UNOS regions between the 2 eras. Competing risk analysis demonstrated that HCC candidates in post-Share 35 era were more likely to die or be delisted for “too sick” while waiting (7.2% vs. 5.3%; p = 0.005) within 15 months. A higher proportion of ECD (p

Suggested Citation

  • Kristopher P Croome & David D Lee & Denise Harnois & C Burcin Taner, 2017. "Effects of the Share 35 Rule on Waitlist and Liver Transplantation Outcomes for Patients with Hepatocellular Carcinoma," PLOS ONE, Public Library of Science, vol. 12(1), pages 1-9, January.
    • Handle: RePEc:plo:pone00:0170673
    DOI: 10.1371/journal.pone.0170673
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