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Association of CKD-MBD Markers with All-Cause Mortality in Prevalent Hemodialysis Patients: A Cohort Study in Beijing

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  • Duo Li
  • Ling Zhang
  • Li Zuo
  • Cheng Gang Jin
  • Wen Ge Li
  • Jin-Bor Chen

Abstract

The relationships between all-cause mortality and serum intact parathyroid hormone (iPTH), calcium, and phosphate are fairly diverse in patients on maintenance hemodialysis according to prior studies. This study evaluated the association of chronic kidney disease-mineral and bone disorder (CKD-MBD) markers with all-cause mortality in prevalent hemodialysis patients from 2007 to 2012 in Beijing, China. A cohort, involving 8530 prevalent hemodialysis patients who had undergone a 6–70 months follow-up program (with median as 40 months) was formed. Related data was recorded from the database in 120 hemodialysis centers of Beijing Health Bureau (2007 to 2012). Information regarding baseline demographics, blood CKD-MBD markers and all-cause mortality was retrospectively reviewed. By using multivariate Cox regression model analysis, patients with a low iPTH level at baseline were found to have greater risk of mortality (

Suggested Citation

  • Duo Li & Ling Zhang & Li Zuo & Cheng Gang Jin & Wen Ge Li & Jin-Bor Chen, 2017. "Association of CKD-MBD Markers with All-Cause Mortality in Prevalent Hemodialysis Patients: A Cohort Study in Beijing," PLOS ONE, Public Library of Science, vol. 12(1), pages 1-10, January.
    • Handle: RePEc:plo:pone00:0168537
    DOI: 10.1371/journal.pone.0168537
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