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Decreased Ovarian Reserve Predicts Inexplicability of Recurrent Miscarriage? A Retrospective Analysis

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  • Sophie Pils
  • Regina Promberger
  • Stephanie Springer
  • Elmar Joura
  • Johannes Ott

Abstract

Objective: To evaluate anti-Mullerian hormone, basal follicle stimulating hormone, luteinizing hormone, estradiol, and female age in women with recurrent miscarriage and to compare women with explained and idiopathic recurrent miscarriage. Design: Retrospective cohort study. Setting: University hospital, tertiary care center. Patients: Women with recurrent miscarriage (78 explained, 66 idiopathic). Intervention(s): None. Main Outcome Measures(s): Anti-Mullerian hormone, basal follicle stimulating hormone, luteinizing hormone, estradiol, and age. Results: Anti-Mullerian hormone and estradiol were significantly lower in women with idiopathic recurrent miscarriage (median 1.2 ng/ml, IQR 0.6–2.1, and median 36.5 pg/ml, IQR 25.8–47.3, respectively) than in women with explained recurrent miscarriage (median 2.0 ng/ml, IQR 1.1–2.7, and median 42.5 pg/ml, IQR 32.8–59.8, respectively; p

Suggested Citation

  • Sophie Pils & Regina Promberger & Stephanie Springer & Elmar Joura & Johannes Ott, 2016. "Decreased Ovarian Reserve Predicts Inexplicability of Recurrent Miscarriage? A Retrospective Analysis," PLOS ONE, Public Library of Science, vol. 11(9), pages 1-7, September.
    • Handle: RePEc:plo:pone00:0161606
    DOI: 10.1371/journal.pone.0161606
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