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Growth factor rattled out of its cage

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  • Taekjip Ha

    (Biomedical Engineering and Biophysics and Biochemistry, Johns Hopkins University, Howard Hughes Medical Institute, Baltimore, Maryland 21205, USA.)

Abstract

The growth factor TGF-ß1 is located inside a protein cage, and is thought to be released by force applied through integrin proteins. A structure of TGF-ß1 in complex with integrin αVß6 sheds light on the uncaging process. See Article p.55

Suggested Citation

  • Taekjip Ha, 2017. "Growth factor rattled out of its cage," Nature, Nature, vol. 542(7639), pages 40-41, February.
    • Handle: RePEc:nat:nature:v:542:y:2017:i:7639:d:10.1038_nature21119
    DOI: 10.1038/nature21119
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