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Insights from studying human sleep disorders

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  • Mark W. Mahowald

    (Minnesota Regional Sleep Disorders Center, and University of MN Medical School)

  • Carlos H. Schenck

    (Minnesota Regional Sleep Disorders Center, and University of MN Medical School)

Abstract

Problems with sleep are one of the commonest reasons for seeking medical attention. Knowledge gained from basic research into sleep in animals has led to marked advances in the understanding of human sleep, with important diagnostic and therapeutic implications. At the same time, research guided by human sleep disorders is leading to important basic sleep concepts. For example, sleep may not be a global, but rather a local, brain phenomenon. Furthermore, contrary to common assumptions, wakefulness, rapid eye movement (REM) and non-REM sleep are not mutually exclusive states. This striking realization explains a fascinating range of clinical phenomena.

Suggested Citation

  • Mark W. Mahowald & Carlos H. Schenck, 2005. "Insights from studying human sleep disorders," Nature, Nature, vol. 437(7063), pages 1279-1285, October.
  • Handle: RePEc:nat:nature:v:437:y:2005:i:7063:d:10.1038_nature04287
    DOI: 10.1038/nature04287
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    Cited by:

    1. Matt T Bianchi & Sydney S Cash & Joseph Mietus & Chung-Kang Peng & Robert Thomas, 2010. "Obstructive Sleep Apnea Alters Sleep Stage Transition Dynamics," PLOS ONE, Public Library of Science, vol. 5(6), pages 1-12, June.

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