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Transportable hyperpolarized metabolites

Author

Listed:
  • Xiao Ji

    (Ecole Polytechnique Fédérale de Lausanne, Institut des Sciences et Ingénierie Chimiques)

  • Aurélien Bornet

    (Ecole Polytechnique Fédérale de Lausanne, Institut des Sciences et Ingénierie Chimiques)

  • Basile Vuichoud

    (Ecole Polytechnique Fédérale de Lausanne, Institut des Sciences et Ingénierie Chimiques)

  • Jonas Milani

    (Ecole Polytechnique Fédérale de Lausanne, Institut des Sciences et Ingénierie Chimiques)

  • David Gajan

    (Univ Lyon, CNRS, Université Claude Bernard Lyon 1, ENS de Lyon, Institut des Sciences Analytiques, UMR 5280, 5 rue de la Doua)

  • Aaron J. Rossini

    (Ecole Polytechnique Fédérale de Lausanne, Institut des Sciences et Ingénierie Chimiques)

  • Lyndon Emsley

    (Ecole Polytechnique Fédérale de Lausanne, Institut des Sciences et Ingénierie Chimiques)

  • Geoffrey Bodenhausen

    (Ecole Polytechnique Fédérale de Lausanne, Institut des Sciences et Ingénierie Chimiques
    Ecole Normale Supérieure, PSL Research University, UPMC Univ Paris 06, CNRS, Laboratoire des Biomolécules (LBM)
    Sorbonne Universités, UPMC Paris 06, Ecole Normale Supérieure, CNRS, Laboratoire des Biomolécules (LBM))

  • Sami Jannin

    (Ecole Polytechnique Fédérale de Lausanne, Institut des Sciences et Ingénierie Chimiques
    Univ Lyon, CNRS, Université Claude Bernard Lyon 1, ENS de Lyon, Institut des Sciences Analytiques, UMR 5280, 5 rue de la Doua)

Abstract

Nuclear spin hyperpolarization of 13C-labelled metabolites by dissolution dynamic nuclear polarization can enhance the NMR signals of metabolites by several orders of magnitude, which has enabled in vivo metabolic imaging by MRI. However, because of the short lifetime of the hyperpolarized magnetization (typically

Suggested Citation

  • Xiao Ji & Aurélien Bornet & Basile Vuichoud & Jonas Milani & David Gajan & Aaron J. Rossini & Lyndon Emsley & Geoffrey Bodenhausen & Sami Jannin, 2017. "Transportable hyperpolarized metabolites," Nature Communications, Nature, vol. 8(1), pages 1-7, April.
    • Handle: RePEc:nat:natcom:v:8:y:2017:i:1:d:10.1038_ncomms13975
    DOI: 10.1038/ncomms13975
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